Quantifying lead-attributable cardiovascular disease burden in the United States

Farah Abdulhai; Issam Motairek; Saeid Mirzai; Basel Bazarbachi; Fatimah Chamseddine; Mohammad Alamer; Pedro RVO Salerno; Mohamed H.E. Makhlouf; Salil V. Deo; Sadeer Al-Kindi

doi:10.1016/j.cpcardiol.2024.102565

Quantifying lead-attributable cardiovascular disease burden in the United States

Farah Abdulhai, Issam Motairek, Saeid Mirzai, Basel Bazarbachi, Fatimah Chamseddine, Mohammad Alamer, Pedro RVO Salerno, Mohamed H.E. Makhlouf, Salil V. Deo, Sadeer Al-Kindi

Academic Institute

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Lead exposure has been linked to a myriad of cardiovascular diseases. Utilizing data from the 2019 Global Burden of Disease Study, we quantified age-standardized lead exposure-related mortality and disability-adjusted life years (DALYs) in the United States between 1990 and 2019. Our analysis revealed a substantial reduction in age-standardized cardiovascular disease (CVD) mortality attributable to lead exposure by 60 % (from 7.4 to 2.9 per 100,000), along with a concurrent decrease in age-standardized CVD DALYs by 66 % (from 143.2 to 48.7 per 100,000).

Original language	English (US)
Article number	102565
Pages (from-to)	102565
Journal	Current Problems in Cardiology
Volume	49
Issue number	6
DOIs	https://doi.org/10.1016/j.cpcardiol.2024.102565
State	Published - Jun 2024

Keywords

Cardiovascular risk assessment
Environmental exposures
Lead-exposure
Disability-Adjusted Life Years
Humans
Middle Aged
Cardiovascular Diseases/epidemiology
Risk Factors
Cost of Illness
Male
Lead Poisoning/epidemiology
Global Burden of Disease
United States/epidemiology
Lead/adverse effects
Adult
Female
Aged
Environmental Exposure/adverse effects

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1016/j.cpcardiol.2024.102565

Cite this

@article{ed52ff8ee20f4e48bf19c6920077c5bb,

title = "Quantifying lead-attributable cardiovascular disease burden in the United States",

abstract = "Lead exposure has been linked to a myriad of cardiovascular diseases. Utilizing data from the 2019 Global Burden of Disease Study, we quantified age-standardized lead exposure-related mortality and disability-adjusted life years (DALYs) in the United States between 1990 and 2019. Our analysis revealed a substantial reduction in age-standardized cardiovascular disease (CVD) mortality attributable to lead exposure by 60 \% (from 7.4 to 2.9 per 100,000), along with a concurrent decrease in age-standardized CVD DALYs by 66 \% (from 143.2 to 48.7 per 100,000).",

keywords = "Cardiovascular risk assessment, Environmental exposures, Lead-exposure, Disability-Adjusted Life Years, Humans, Middle Aged, Cardiovascular Diseases/epidemiology, Risk Factors, Cost of Illness, Male, Lead Poisoning/epidemiology, Global Burden of Disease, United States/epidemiology, Lead/adverse effects, Adult, Female, Aged, Environmental Exposure/adverse effects",

author = "Farah Abdulhai and Issam Motairek and Saeid Mirzai and Basel Bazarbachi and Fatimah Chamseddine and Mohammad Alamer and Salerno, \{Pedro RVO\} and Makhlouf, \{Mohamed H.E.\} and Deo, \{Salil V.\} and Sadeer Al-Kindi",

note = "Copyright {\textcopyright} 2024. Published by Elsevier Inc.",

year = "2024",

month = jun,

doi = "10.1016/j.cpcardiol.2024.102565",

language = "English (US)",

volume = "49",

pages = "102565",

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T1 - Quantifying lead-attributable cardiovascular disease burden in the United States

AU - Abdulhai, Farah

AU - Motairek, Issam

AU - Mirzai, Saeid

AU - Bazarbachi, Basel

AU - Chamseddine, Fatimah

AU - Alamer, Mohammad

AU - Salerno, Pedro RVO

AU - Makhlouf, Mohamed H.E.

AU - Deo, Salil V.

AU - Al-Kindi, Sadeer

PY - 2024/6

Y1 - 2024/6

N2 - Lead exposure has been linked to a myriad of cardiovascular diseases. Utilizing data from the 2019 Global Burden of Disease Study, we quantified age-standardized lead exposure-related mortality and disability-adjusted life years (DALYs) in the United States between 1990 and 2019. Our analysis revealed a substantial reduction in age-standardized cardiovascular disease (CVD) mortality attributable to lead exposure by 60 % (from 7.4 to 2.9 per 100,000), along with a concurrent decrease in age-standardized CVD DALYs by 66 % (from 143.2 to 48.7 per 100,000).

AB - Lead exposure has been linked to a myriad of cardiovascular diseases. Utilizing data from the 2019 Global Burden of Disease Study, we quantified age-standardized lead exposure-related mortality and disability-adjusted life years (DALYs) in the United States between 1990 and 2019. Our analysis revealed a substantial reduction in age-standardized cardiovascular disease (CVD) mortality attributable to lead exposure by 60 % (from 7.4 to 2.9 per 100,000), along with a concurrent decrease in age-standardized CVD DALYs by 66 % (from 143.2 to 48.7 per 100,000).

KW - Cardiovascular risk assessment

KW - Environmental exposures

KW - Lead-exposure

KW - Disability-Adjusted Life Years

KW - Humans

KW - Middle Aged

KW - Cardiovascular Diseases/epidemiology

KW - Risk Factors

KW - Cost of Illness

KW - Male

KW - Lead Poisoning/epidemiology

KW - Global Burden of Disease

KW - United States/epidemiology

KW - Lead/adverse effects

KW - Adult

KW - Female

KW - Aged

KW - Environmental Exposure/adverse effects

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M1 - 102565

ER -

Quantifying lead-attributable cardiovascular disease burden in the United States

Abstract

Keywords

ASJC Scopus subject areas

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