Quantifying lead-attributable cardiovascular disease burden in the United States

Farah Abdulhai, Issam Motairek, Saeid Mirzai, Basel Bazarbachi, Fatimah Chamseddine, Mohammad Alamer, Pedro RVO Salerno, Mohamed H.E. Makhlouf, Salil V. Deo, Sadeer Al-Kindi

Research output: Contribution to journalReview articlepeer-review

Abstract

Lead exposure has been linked to a myriad of cardiovascular diseases. Utilizing data from the 2019 Global Burden of Disease Study, we quantified age-standardized lead exposure-related mortality and disability-adjusted life years (DALYs) in the United States between 1990 and 2019. Our analysis revealed a substantial reduction in age-standardized cardiovascular disease (CVD) mortality attributable to lead exposure by 60 % (from 7.4 to 2.9 per 100,000), along with a concurrent decrease in age-standardized CVD DALYs by 66 % (from 143.2 to 48.7 per 100,000).

Original languageEnglish (US)
Article number102565
JournalCurrent Problems in Cardiology
Volume49
Issue number6
DOIs
StatePublished - Jun 2024

Keywords

  • Cardiovascular risk assessment
  • Environmental exposures
  • Lead-exposure

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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