Quantification of myocardial perfusion with MRI and exogenous contrast agents

J. P. Vallée; Henry Dirk Sostman; J. R. Mac Fall; R. E. Coleman

doi:10.1159/000177315

Quantification of myocardial perfusion with MRI and exogenous contrast agents

J. P. Vallée, Henry Dirk Sostman, J. R. Mac Fall, R. E. Coleman

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23 Scopus citations

Abstract

This review discusses the applications of MRI to quantification of the myocardial perfusion. The first step of the measurement is to obtain a concentration-time curve from a signal intensity-time (SI) curve. Factors which influence the correlation between SI and the concentration are discussed for relaxivity and susceptibility agents. The second stage of measurement is to extract parameters of myocardial perfusion from the concentration-time curve. Two methods are considered, one for an intravascular agent and the other for an extravascular agent. Key points are illustrated with experimental data.

Original language	English (US)
Pages (from-to)	90-105
Number of pages	16
Journal	Cardiology (Switzerland)
Volume	88
Issue number	1
DOIs	https://doi.org/10.1159/000177315
State	Published - Jan 1 1997

Keywords

Media model
MRI contrast
Myocardium
Perfusion

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1159/000177315

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abstract = "This review discusses the applications of MRI to quantification of the myocardial perfusion. The first step of the measurement is to obtain a concentration-time curve from a signal intensity-time (SI) curve. Factors which influence the correlation between SI and the concentration are discussed for relaxivity and susceptibility agents. The second stage of measurement is to extract parameters of myocardial perfusion from the concentration-time curve. Two methods are considered, one for an intravascular agent and the other for an extravascular agent. Key points are illustrated with experimental data.",

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AB - This review discusses the applications of MRI to quantification of the myocardial perfusion. The first step of the measurement is to obtain a concentration-time curve from a signal intensity-time (SI) curve. Factors which influence the correlation between SI and the concentration are discussed for relaxivity and susceptibility agents. The second stage of measurement is to extract parameters of myocardial perfusion from the concentration-time curve. Two methods are considered, one for an intravascular agent and the other for an extravascular agent. Key points are illustrated with experimental data.

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KW - Myocardium

KW - Perfusion

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Quantification of myocardial perfusion with MRI and exogenous contrast agents

Abstract

Keywords

ASJC Scopus subject areas

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