Quantification of mitral regurgitation with MR phase-velocity mapping using a control volume method

George P. Chatzimavroudis, John N. Oshinski, Roderic I. Pettigrew, Peter G. Walker, Robert H. Franch, Ajit P. Yoganathan

Research output: Contribution to journalArticlepeer-review

32 Scopus citations


Reliable diagnosis and quantification of mitral regurgitation are important for patient management and for optimizing the time for surgery. Previous methods have often provided suboptimal results. The aim of this in vitro study was to evaluate MR phase-velocity mapping in quantifying the mitral regurgitant volume (MRV) using a control volume (CV) method. A number of contiguous slices were acquired with all three velocity components measured. A CV was then selected, encompassing the regurgitant orifice. Mass conservation dictates that the net inflow into the CV should be equal to the regurgitant flow. Results showed that a CV, the boundary voxels of which excluded the region of flow acceleration and aliasing at the orifice, provided accurate measurements of the regurgitant flow. A smaller CV provided erroneous results because of flow acceleration and velocity aliasing close to the orifice. A large CV generally provided inaccurate results because of reduced velocity sensitivity far from the orifice. Aortic outflow, orifice shape, and valve geometry did not affect the accuracy of the CV measurements. The CV method is a promising approach to the problem of quantification of the MRV.

Original languageEnglish (US)
Pages (from-to)577-582
Number of pages6
JournalJournal of Magnetic Resonance Imaging
Issue number3
StatePublished - May 1998


  • Aortic outflow
  • Control volume
  • Mitral regurgitation
  • Regurgitant volume

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


Dive into the research topics of 'Quantification of mitral regurgitation with MR phase-velocity mapping using a control volume method'. Together they form a unique fingerprint.

Cite this