TY - JOUR
T1 - Pulmonary sarcoidosis following stem cell transplantation
T2 - Is it more than a chance occurrence?
AU - Bhagat, Rajesh
AU - Rizzieri, David A.
AU - Vredenburgh, James J.
AU - Chao, Nelson J.
AU - Folz, Rodney J.
N1 - Funding Information:
This work is funded in part by National Institutes of Health, National Research Service Award HL-07538 to R.B. and Grant HL-55166 to R.J.F.
PY - 2004/8
Y1 - 2004/8
N2 - Noninfectious pulmonary complications are one of the major side effects of hematopoetic stem cell transplant (HSCT); however, the development of pulmonary sarcoidosis post-HSCT is uncommon, with only three cases previously reported. In each of those cases, sarcoidosis was also diagnosed in the stem cell donor. We now report four cases of de novo pulmonary sarcoidosis occurring post-HSCT (3 autologous HSCT and 1 allogeneic HSCT). We suggest that pulmonary sarcoidosis may develop following either autologous or alogeneic HSCT, and the prevalence may be 10-fold higher than that of the normal population.
AB - Noninfectious pulmonary complications are one of the major side effects of hematopoetic stem cell transplant (HSCT); however, the development of pulmonary sarcoidosis post-HSCT is uncommon, with only three cases previously reported. In each of those cases, sarcoidosis was also diagnosed in the stem cell donor. We now report four cases of de novo pulmonary sarcoidosis occurring post-HSCT (3 autologous HSCT and 1 allogeneic HSCT). We suggest that pulmonary sarcoidosis may develop following either autologous or alogeneic HSCT, and the prevalence may be 10-fold higher than that of the normal population.
KW - Bone marrow transplant
KW - Granuloma
KW - Sarcoid
KW - Stem cell transplant
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UR - http://www.scopus.com/inward/citedby.url?scp=4143068039&partnerID=8YFLogxK
U2 - 10.1378/chest.126.2.642
DO - 10.1378/chest.126.2.642
M3 - Article
C2 - 15302757
AN - SCOPUS:4143068039
SN - 0012-3692
VL - 126
SP - 642
EP - 644
JO - CHEST
JF - CHEST
IS - 2
ER -