Pulmonary sarcoidosis following stem cell transplantation: Is it more than a chance occurrence?

Rajesh Bhagat; David A. Rizzieri; James J. Vredenburgh; Nelson J. Chao; Rodney J. Folz

doi:10.1378/chest.126.2.642

Pulmonary sarcoidosis following stem cell transplantation: Is it more than a chance occurrence?

Rajesh Bhagat, David A. Rizzieri, James J. Vredenburgh, Nelson J. Chao, Rodney J. Folz

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

Noninfectious pulmonary complications are one of the major side effects of hematopoetic stem cell transplant (HSCT); however, the development of pulmonary sarcoidosis post-HSCT is uncommon, with only three cases previously reported. In each of those cases, sarcoidosis was also diagnosed in the stem cell donor. We now report four cases of de novo pulmonary sarcoidosis occurring post-HSCT (3 autologous HSCT and 1 allogeneic HSCT). We suggest that pulmonary sarcoidosis may develop following either autologous or alogeneic HSCT, and the prevalence may be 10-fold higher than that of the normal population.

Original language	English (US)
Pages (from-to)	642-644
Number of pages	3
Journal	CHEST
Volume	126
Issue number	2
DOIs	https://doi.org/10.1378/chest.126.2.642
State	Published - Aug 2004

Keywords

Bone marrow transplant
Granuloma
Sarcoid
Stem cell transplant

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine
Critical Care and Intensive Care Medicine
Cardiology and Cardiovascular Medicine

Access to Document

10.1378/chest.126.2.642

Cite this

@article{ea9c19e481144506bc2ada9c2afc0a15,

title = "Pulmonary sarcoidosis following stem cell transplantation: Is it more than a chance occurrence?",

abstract = "Noninfectious pulmonary complications are one of the major side effects of hematopoetic stem cell transplant (HSCT); however, the development of pulmonary sarcoidosis post-HSCT is uncommon, with only three cases previously reported. In each of those cases, sarcoidosis was also diagnosed in the stem cell donor. We now report four cases of de novo pulmonary sarcoidosis occurring post-HSCT (3 autologous HSCT and 1 allogeneic HSCT). We suggest that pulmonary sarcoidosis may develop following either autologous or alogeneic HSCT, and the prevalence may be 10-fold higher than that of the normal population.",

keywords = "Bone marrow transplant, Granuloma, Sarcoid, Stem cell transplant",

author = "Rajesh Bhagat and Rizzieri, {David A.} and Vredenburgh, {James J.} and Chao, {Nelson J.} and Folz, {Rodney J.}",

note = "Funding Information: This work is funded in part by National Institutes of Health, National Research Service Award HL-07538 to R.B. and Grant HL-55166 to R.J.F. Copyright: Copyright 2017 Elsevier B.V., All rights reserved.",

year = "2004",

month = aug,

doi = "10.1378/chest.126.2.642",

language = "English (US)",

volume = "126",

pages = "642--644",

journal = "CHEST",

issn = "0012-3692",

publisher = "American College of Chest Physicians",

number = "2",

}

TY - JOUR

T1 - Pulmonary sarcoidosis following stem cell transplantation

T2 - Is it more than a chance occurrence?

AU - Bhagat, Rajesh

AU - Rizzieri, David A.

AU - Vredenburgh, James J.

AU - Chao, Nelson J.

AU - Folz, Rodney J.

N1 - Funding Information: This work is funded in part by National Institutes of Health, National Research Service Award HL-07538 to R.B. and Grant HL-55166 to R.J.F. Copyright: Copyright 2017 Elsevier B.V., All rights reserved.

PY - 2004/8

Y1 - 2004/8

N2 - Noninfectious pulmonary complications are one of the major side effects of hematopoetic stem cell transplant (HSCT); however, the development of pulmonary sarcoidosis post-HSCT is uncommon, with only three cases previously reported. In each of those cases, sarcoidosis was also diagnosed in the stem cell donor. We now report four cases of de novo pulmonary sarcoidosis occurring post-HSCT (3 autologous HSCT and 1 allogeneic HSCT). We suggest that pulmonary sarcoidosis may develop following either autologous or alogeneic HSCT, and the prevalence may be 10-fold higher than that of the normal population.

AB - Noninfectious pulmonary complications are one of the major side effects of hematopoetic stem cell transplant (HSCT); however, the development of pulmonary sarcoidosis post-HSCT is uncommon, with only three cases previously reported. In each of those cases, sarcoidosis was also diagnosed in the stem cell donor. We now report four cases of de novo pulmonary sarcoidosis occurring post-HSCT (3 autologous HSCT and 1 allogeneic HSCT). We suggest that pulmonary sarcoidosis may develop following either autologous or alogeneic HSCT, and the prevalence may be 10-fold higher than that of the normal population.

KW - Bone marrow transplant

KW - Granuloma

KW - Sarcoid

KW - Stem cell transplant

UR - http://www.scopus.com/inward/record.url?scp=4143068039&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=4143068039&partnerID=8YFLogxK

U2 - 10.1378/chest.126.2.642

DO - 10.1378/chest.126.2.642

M3 - Article

C2 - 15302757

AN - SCOPUS:4143068039

VL - 126

SP - 642

EP - 644

JO - CHEST

JF - CHEST

SN - 0012-3692

IS - 2

ER -

Pulmonary sarcoidosis following stem cell transplantation: Is it more than a chance occurrence?

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this