Pulmonary invasive aspergillosis in patients infected with the human immunodeficiency virus: Report of two cases

Eleftherios Mylonakis; Maria D. Mileno; Timothy Flanigan; Douglas F. De Orchis; Josiah Rich

doi:10.1016/S0147-9563(98)90071-1

Pulmonary invasive aspergillosis in patients infected with the human immunodeficiency virus: Report of two cases

Eleftherios Mylonakis, Maria D. Mileno, Timothy Flanigan, Douglas F. De Orchis, Josiah Rich

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Patients infected with the human immunodeficiency virus (HIV) have an increased frequency of invasive aspergillosis. We report two cases of invasive pulmonary aspergillosis in patients infected with HIV. Patients had less than 10 CD₄ (helper cell) cells/mm³ (2/2), presented with fever (2/2), dyspnea (1/2), and abnormal chest radiograph (2/2). Diagnosis was established by transbronchial biopsy (1/2) and autopsy (1/2). Patients died in spite of treatment with intravenous deoxycholate amphotericin B. Prognosis of invasive pulmonary aspergillosis among patients infected with HIV remains dismal, even with aggressive antifungal treatment.

Original language	English (US)
Pages (from-to)	63-66
Number of pages	4
Journal	Heart and Lung: Journal of Acute and Critical Care
Volume	27
Issue number	1
DOIs	https://doi.org/10.1016/S0147-9563(98)90071-1
State	Published - 1998

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine
Critical Care and Intensive Care Medicine
Cardiology and Cardiovascular Medicine

Divisions

Infectious Disease

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10.1016/S0147-9563(98)90071-1

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title = "Pulmonary invasive aspergillosis in patients infected with the human immunodeficiency virus: Report of two cases",

abstract = "Patients infected with the human immunodeficiency virus (HIV) have an increased frequency of invasive aspergillosis. We report two cases of invasive pulmonary aspergillosis in patients infected with HIV. Patients had less than 10 CD4 (helper cell) cells/mm3 (2/2), presented with fever (2/2), dyspnea (1/2), and abnormal chest radiograph (2/2). Diagnosis was established by transbronchial biopsy (1/2) and autopsy (1/2). Patients died in spite of treatment with intravenous deoxycholate amphotericin B. Prognosis of invasive pulmonary aspergillosis among patients infected with HIV remains dismal, even with aggressive antifungal treatment.",

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T1 - Pulmonary invasive aspergillosis in patients infected with the human immunodeficiency virus

T2 - Report of two cases

AU - Mylonakis, Eleftherios

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AU - Flanigan, Timothy

AU - De Orchis, Douglas F.

AU - Rich, Josiah

PY - 1998

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AB - Patients infected with the human immunodeficiency virus (HIV) have an increased frequency of invasive aspergillosis. We report two cases of invasive pulmonary aspergillosis in patients infected with HIV. Patients had less than 10 CD4 (helper cell) cells/mm3 (2/2), presented with fever (2/2), dyspnea (1/2), and abnormal chest radiograph (2/2). Diagnosis was established by transbronchial biopsy (1/2) and autopsy (1/2). Patients died in spite of treatment with intravenous deoxycholate amphotericin B. Prognosis of invasive pulmonary aspergillosis among patients infected with HIV remains dismal, even with aggressive antifungal treatment.

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Pulmonary invasive aspergillosis in patients infected with the human immunodeficiency virus: Report of two cases

Abstract

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