Pulmonary hypertension due to high cardiac output

Kanza N. Qaiser, Sandeep Sahay, Adriano R. Tonelli

Research output: Contribution to journalReview articlepeer-review

Abstract

Pulmonary hypertension (PH) is usually associated with a normal or decreased cardiac output (CO). Less commonly, PH can occur in the context of a hyperdynamic circulation, characterized by high CO (>8 L/min) and/or cardiac index ≥4 L/min/m2 in the setting of a decreased systemic vascular resistance. PH due to high CO can occur due to multiple conditions and in general remains understudied. In this review article we describe the pathophysiology, etiology, diagnosis, hemodynamic characteristics, and management of PH in the setting of high CO. It is important to recognize this distinct entity as PH tends to improve with treatment of the underlying etiology and PH specific therapies may worsen the hemodynamic state.

Original languageEnglish (US)
Article number107034
JournalRespiratory Medicine
Volume206
DOIs
StatePublished - Jan 2023

Keywords

  • High cardiac output
  • Hyperdynamic state
  • Pulmonary hypertension

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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