TY - JOUR
T1 - Pulmonary blastoma with rhabdomyosarcomatous differentiation
T2 - An electron microscopic and immunohistochemical study
AU - Heckman, C. J.
AU - Truong, Luan
AU - Cagle, Philip T.
AU - Font, R. L.
PY - 1988/1/1
Y1 - 1988/1/1
N2 - Pulmonary blastoma is a rare lung tumor composed of epithelial and mesenchymal elements; the latter element may show various patterns of differentiation toward mature tissue, such as cartilage, smooth muscle, and bone. Rhabdomyoblastic differentiation in pulmonary blastoma is quite rare; only five such cases have been reported. We report two cases of pulmonary blastoma with rhabdomyoblastic differentiation documented for the first time by electron microscopy and immunohistochemistry including documentation for myoglobin, actin, vimentin and desmin. The diffuse and prominent rhabdomyoblastic differentiation in one case is most unusual.
AB - Pulmonary blastoma is a rare lung tumor composed of epithelial and mesenchymal elements; the latter element may show various patterns of differentiation toward mature tissue, such as cartilage, smooth muscle, and bone. Rhabdomyoblastic differentiation in pulmonary blastoma is quite rare; only five such cases have been reported. We report two cases of pulmonary blastoma with rhabdomyoblastic differentiation documented for the first time by electron microscopy and immunohistochemistry including documentation for myoglobin, actin, vimentin and desmin. The diffuse and prominent rhabdomyoblastic differentiation in one case is most unusual.
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U2 - 10.1097/00000478-198801000-00005
DO - 10.1097/00000478-198801000-00005
M3 - Article
C2 - 3337338
AN - SCOPUS:0023857269
SN - 0147-5185
VL - 12
SP - 35
EP - 40
JO - American Journal of Surgical Pathology
JF - American Journal of Surgical Pathology
IS - 1
ER -