TY - JOUR
T1 - Proton relaxation rates of water in brain and brain tumors
AU - Parrish, Rob G.
AU - Kurland, Robert J.
AU - Janese, Woodrow W.
AU - Bakay, Louis
PY - 1974/1/1
Y1 - 1974/1/1
N2 - The distribution of relaxation rates of water in "normal" (autopsy) samples of canine and human brain shows considerable overlap with that for brain tumor samples. The following ranges of values for the spin-spin relaxation rates were observed: for normal brain gray matter, 8.6 to 11.3 sec-1 (mean, 9.5 sec-1); for normal brain white matter, 13.3 to 15.7 sec-1 (mean, 15.5 sec-1); for six types of malignant tumor, 4.8 to 13.4 sec-1 (mean, 9.3 sec-1); for five types of benign tumor, 7.1 to 16.4 sec-1 (mean, 11.5 sec -1). Spin-lattice relaxation rates showed a similar pattern. At least two nonexchanging water components with different relaxation rates were indicated by the analysis of the spin-spin relaxation measurements for the white matter samples.
AB - The distribution of relaxation rates of water in "normal" (autopsy) samples of canine and human brain shows considerable overlap with that for brain tumor samples. The following ranges of values for the spin-spin relaxation rates were observed: for normal brain gray matter, 8.6 to 11.3 sec-1 (mean, 9.5 sec-1); for normal brain white matter, 13.3 to 15.7 sec-1 (mean, 15.5 sec-1); for six types of malignant tumor, 4.8 to 13.4 sec-1 (mean, 9.3 sec-1); for five types of benign tumor, 7.1 to 16.4 sec-1 (mean, 11.5 sec -1). Spin-lattice relaxation rates showed a similar pattern. At least two nonexchanging water components with different relaxation rates were indicated by the analysis of the spin-spin relaxation measurements for the white matter samples.
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U2 - 10.1126/science.183.4123.438
DO - 10.1126/science.183.4123.438
M3 - Article
C2 - 4358077
AN - SCOPUS:0015981362
SN - 0036-8075
VL - 183
SP - 438
EP - 439
JO - Science
JF - Science
IS - 4123
ER -