Protein immobilization on 3C-SiC (100) as a substrate for detecting the onset of acute myocardial infarction (AMI)

A. Oliveros; A. Guiseppi-Elie; M. Jaroszeski; S. E. Saddow

doi:10.1109/EMBC.2012.6346261

Protein immobilization on 3C-SiC (100) as a substrate for detecting the onset of acute myocardial infarction (AMI)

A. Oliveros, A. Guiseppi-Elie, M. Jaroszeski, S. E. Saddow

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

4 Scopus citations

Abstract

Silicon Carbide (SiC), has been shown to be a bio- and hema-compatible substrate that could potentially be used in biosensor applications. The development of a viable biorecognition interface using SiC as the substrate material for bio-detection is described. Surface modification with 3-aminopropyltriethoxysilane (APTES) and immobilization via covalent conjugation of antimyoglobin (anti-Myo) on the modified surfaces is achieved, which are initial steps for immunosensing based devices. Successful formation of APTES layers and antibody immobilization were identified with surface water contact angle (SWCA), X-ray photoelectron spectroscopy (XPS) and atomic force microscopy (AFM).

Original language	English (US)
Title of host publication	2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2012
Pages	1643-1646
Number of pages	4
DOIs	https://doi.org/10.1109/EMBC.2012.6346261
State	Published - 2012
Event	34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2012 - San Diego, CA, United States Duration: Aug 28 2012 → Sep 1 2012

Publication series

Name	Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
ISSN (Print)	1557-170X

Other

Other	34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2012
Country/Territory	United States
City	San Diego, CA
Period	8/28/12 → 9/1/12

ASJC Scopus subject areas

Signal Processing
Biomedical Engineering
Computer Vision and Pattern Recognition
Health Informatics

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10.1109/EMBC.2012.6346261

Cite this

Oliveros, A., Guiseppi-Elie, A., Jaroszeski, M., & Saddow, S. E. (2012). Protein immobilization on 3C-SiC (100) as a substrate for detecting the onset of acute myocardial infarction (AMI). In 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2012 (pp. 1643-1646). [6346261] (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). https://doi.org/10.1109/EMBC.2012.6346261

Protein immobilization on 3C-SiC (100) as a substrate for detecting the onset of acute myocardial infarction (AMI). / Oliveros, A.; Guiseppi-Elie, A.; Jaroszeski, M. et al.

2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2012. 2012. p. 1643-1646 6346261 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Oliveros, A, Guiseppi-Elie, A, Jaroszeski, M & Saddow, SE 2012, Protein immobilization on 3C-SiC (100) as a substrate for detecting the onset of acute myocardial infarction (AMI). in 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2012., 6346261, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, pp. 1643-1646, 34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2012, San Diego, CA, United States, 8/28/12. https://doi.org/10.1109/EMBC.2012.6346261

Oliveros A, Guiseppi-Elie A, Jaroszeski M, Saddow SE. Protein immobilization on 3C-SiC (100) as a substrate for detecting the onset of acute myocardial infarction (AMI). In 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2012. 2012. p. 1643-1646. 6346261. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). https://doi.org/10.1109/EMBC.2012.6346261

Oliveros, A. ; Guiseppi-Elie, A. ; Jaroszeski, M. et al. / Protein immobilization on 3C-SiC (100) as a substrate for detecting the onset of acute myocardial infarction (AMI). 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2012. 2012. pp. 1643-1646 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).

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Protein immobilization on 3C-SiC (100) as a substrate for detecting the onset of acute myocardial infarction (AMI)

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