Prostatic transitional cell carcinoma: Pathologic features and clinical management

Steven Shen, Seth P. Lerner

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations


Prostatic involvement by transitional cell carcinoma (pTCC) in patients with bladder cancer is a frequent finding, particularly in patients with high-grade invasive tumor and urothelial carcinoma in situ. Various patterns and levels of prostatic involvement have been described, and their impact in patients' management and their prognosis recognized. The role of prostatic urethral biopsy and intraoperative frozen section in the management of bladder cancer, tailoring to the bladder tumor stage is still not well defined and universally accepted. This review discusses the current understanding of the biology and histological patterns of p TCC and their clinical significance and management options. A rational approach for management of p TCC in patients with bladder cancer will be proposed on the basis of our experience and our review of literature.

Original languageEnglish (US)
Pages (from-to)1155-1162
Number of pages8
JournalExpert Review of Anticancer Therapy
Issue number8
StatePublished - Aug 2007


  • Bladder cancer
  • Prostatic transitional cell carcinoma
  • pTCC

ASJC Scopus subject areas

  • Pharmacology
  • Cancer Research


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