Proof-of-concept modular fluid handling prototype integrated with microfluidic biochemical assay modules for point-of-care testing

Shivani Sathish, Kazumi Toda-Peters, Amy Q. Shen

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

Large populations around the world suffer from numerous but treatable health issues, caused by either lifestyle choices or environmental factors. Over the past decades, point-of-care testing kits have been developed to circumvent the reliance on laboratories, by allowing users to perform preliminary health or environmental testing from the privacy of their homes. However, these kits heavily rely on the precision of the user to perform the procedures, leading to increased variability in final assessments. To eliminate user-induced errors, we present an integrated, completely sealed, and disposable point-of-care testing prototype that exploits the benefits of microfluidics and 3D-printing fabrication techniques. The palm-sized modular prototype consists of a manually operated fluid handling device that allows precise mixing, filtration, and delivery of fluids to an on-board microfluidic assay unit for subsequent detection of specific biochemical analytes, with a minimized risk of contamination.

Original languageEnglish (US)
Article numbere1
JournalVIEW
Volume1
Issue number1
DOIs
StatePublished - Mar 2020

ASJC Scopus subject areas

  • Biomaterials
  • Biomedical Engineering

Fingerprint

Dive into the research topics of 'Proof-of-concept modular fluid handling prototype integrated with microfluidic biochemical assay modules for point-of-care testing'. Together they form a unique fingerprint.

Cite this