TY - JOUR
T1 - Prolonged Ambulatory Antroduodenal Manometry in Humans
AU - Wilson, Paul
AU - Perdikis, Galen
AU - Hinder, Ronald A.
AU - Redmond, Elizabeth J.
AU - Anselmino, Marco
AU - Quigley, Eanionn M.M.
N1 - Copyright:
Copyright 2016 Elsevier B.V., All rights reserved.
PY - 1994/9
Y1 - 1994/9
N2 - Objectives: To perform prolonged ambulatory recordings of antroduodenal motor activity in humans. Methods: Antroduodenal manometric recordings were performed in 20 normal subjects (12 male, eight female, ages 19-41 years), using a 5-channel solid state catheter assembly (three antral, two duodenal transducers) positioned under fluoroscopy. A glass electrode simultaneously recorded pH in the antrum. Results: Continuous, simultaneous recordings of antral and duodenal motor activity were obtained for 22.5 ± 0.3 h. During fasting, 131 complete migrating motor complexes (MMCs) were recorded (6.6 ± 0.9/subject). The average interval from onset of recording to completion of the first MMC cycle was 498 ± 19.24 minutes. Significant diurnal variations were observed in MMC frequency (awake vs asleep: 0.25/subject/h vs 0.64/subject/h; p < 0.05), period (shorter during sleep), phase I duration (longer during sleep), and phase II duration (shorter during sleep). Among females, MMCs were more frequent and shorter. After meal administration, duodenal recording sites demonstrated a typical 'fed' response; antral distension and/or retrograde catheter movement, on meal ingestion, however, precluded reliable antral 'fed' recordings. Conclusions: Prolonged ambulatory antroduodenal manometry provides detailed and reliable information on fasting antral and duodenal motor activity, antral distension, and/or retrograde catheter migration on meal ingestion; there are limits, however, to the usefulness of this methodology for the evaluation of the fed motor response in the antrum.
AB - Objectives: To perform prolonged ambulatory recordings of antroduodenal motor activity in humans. Methods: Antroduodenal manometric recordings were performed in 20 normal subjects (12 male, eight female, ages 19-41 years), using a 5-channel solid state catheter assembly (three antral, two duodenal transducers) positioned under fluoroscopy. A glass electrode simultaneously recorded pH in the antrum. Results: Continuous, simultaneous recordings of antral and duodenal motor activity were obtained for 22.5 ± 0.3 h. During fasting, 131 complete migrating motor complexes (MMCs) were recorded (6.6 ± 0.9/subject). The average interval from onset of recording to completion of the first MMC cycle was 498 ± 19.24 minutes. Significant diurnal variations were observed in MMC frequency (awake vs asleep: 0.25/subject/h vs 0.64/subject/h; p < 0.05), period (shorter during sleep), phase I duration (longer during sleep), and phase II duration (shorter during sleep). Among females, MMCs were more frequent and shorter. After meal administration, duodenal recording sites demonstrated a typical 'fed' response; antral distension and/or retrograde catheter movement, on meal ingestion, however, precluded reliable antral 'fed' recordings. Conclusions: Prolonged ambulatory antroduodenal manometry provides detailed and reliable information on fasting antral and duodenal motor activity, antral distension, and/or retrograde catheter migration on meal ingestion; there are limits, however, to the usefulness of this methodology for the evaluation of the fed motor response in the antrum.
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U2 - 10.1111/j.1572-0241.1994.tb09165.x
DO - 10.1111/j.1572-0241.1994.tb09165.x
M3 - Article
C2 - 8079926
AN - SCOPUS:0027985442
VL - 89
SP - 1489
EP - 1495
JO - American Journal of Gastroenterology
JF - American Journal of Gastroenterology
SN - 0002-9270
IS - 9
ER -