PROLIFERATIVE ACTINIC KERATOSIS

Leonard Harry Goldberg, AARON K. JOSEPH, JAIME A. TSCHEN

Research output: Contribution to journalArticle

44 Scopus citations

Abstract

Background. Solar/actinic keratoses (AKS) are premalignant lesions, usually less than 1 cm in diameter, that appear on chronically sun-damaged skin. Methods. We describe four patients with a form of AK that enlarged and recurred despite standard treatment. Histologic examination revealed a single and multilayered sheet of anaplastic cells along the undersurface of the epidermis extending down hair follicles and present over a large area. Results. Three of the patients developed either a squamous cell carcinoma (SCC) or basal cell carcinoma (BCC) within the area encompassed by the AK. Conclusions. These cases represent an insidious, proliferative form of AK with an increased tendency to develop into skin cancer.

Original languageEnglish (US)
Pages (from-to)341-345
Number of pages5
JournalInternational Journal of Dermatology
Volume33
Issue number5
DOIs
StatePublished - Jan 1 1994

ASJC Scopus subject areas

  • Dermatology

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