Prolactin-like immunoreactivity: Localization in nerve terminals of rat hypothalamus

Kjell Fuxe; Tomas Hökfelt; Peter Eneroth; Jan-Ake Gustafsson; Paul Skett

doi:10.1126/science.323973

Prolactin-like immunoreactivity: Localization in nerve terminals of rat hypothalamus

Kjell Fuxe, Tomas Hökfelt, Peter Eneroth, Jan-Ake Gustafsson, Paul Skett

Houston Methodist

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Abstract

Antibodies to rat prolactin were used in immunohistochemical studies of the hypothalamus and preoptic area of the rat. Evidence was obtained that a protein immunochemically related to prolactin was stored in networks of nerve terminals of many hypothalamic areas such as the arcuate nucleus, the dorsomedial hypothalamic nucleus, and periventricular regions of the hypothalamus and preoptic area. The neuronal storage of a prolactin like protein in the hypothalamus was unaffected by hypophysectomy.

Original language	English (US)
Pages (from-to)	899-900
Number of pages	2
Journal	Science
Volume	196
Issue number	4292
DOIs	https://doi.org/10.1126/science.323973
State	Published - Jan 1 1977

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title = "Prolactin-like immunoreactivity: Localization in nerve terminals of rat hypothalamus",

abstract = "Antibodies to rat prolactin were used in immunohistochemical studies of the hypothalamus and preoptic area of the rat. Evidence was obtained that a protein immunochemically related to prolactin was stored in networks of nerve terminals of many hypothalamic areas such as the arcuate nucleus, the dorsomedial hypothalamic nucleus, and periventricular regions of the hypothalamus and preoptic area. The neuronal storage of a prolactin like protein in the hypothalamus was unaffected by hypophysectomy.",

author = "Kjell Fuxe and Tomas H{\"o}kfelt and Peter Eneroth and Jan-Ake Gustafsson and Paul Skett",

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T1 - Prolactin-like immunoreactivity

T2 - Localization in nerve terminals of rat hypothalamus

AU - Fuxe, Kjell

AU - Hökfelt, Tomas

AU - Eneroth, Peter

AU - Gustafsson, Jan-Ake

AU - Skett, Paul

PY - 1977/1/1

Y1 - 1977/1/1

N2 - Antibodies to rat prolactin were used in immunohistochemical studies of the hypothalamus and preoptic area of the rat. Evidence was obtained that a protein immunochemically related to prolactin was stored in networks of nerve terminals of many hypothalamic areas such as the arcuate nucleus, the dorsomedial hypothalamic nucleus, and periventricular regions of the hypothalamus and preoptic area. The neuronal storage of a prolactin like protein in the hypothalamus was unaffected by hypophysectomy.

AB - Antibodies to rat prolactin were used in immunohistochemical studies of the hypothalamus and preoptic area of the rat. Evidence was obtained that a protein immunochemically related to prolactin was stored in networks of nerve terminals of many hypothalamic areas such as the arcuate nucleus, the dorsomedial hypothalamic nucleus, and periventricular regions of the hypothalamus and preoptic area. The neuronal storage of a prolactin like protein in the hypothalamus was unaffected by hypophysectomy.

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SP - 899

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JO - Science

JF - Science

IS - 4292

ER -

Prolactin-like immunoreactivity: Localization in nerve terminals of rat hypothalamus

Abstract

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