TY - JOUR
T1 - Prognostic impact of mechanical ventilation after liver transplantation
T2 - A national database study
AU - Yuan, Hui
AU - Tuttle-Newhall, Janet E.
AU - Chawa, Vikram
AU - Schnitzler, Mark A.
AU - Xiao, Huiling
AU - Axelrod, David
AU - Dzebisashvili, Nino
AU - Lentine, Krista L.
N1 - Funding Information:
This work was supported in part by grants from the National Institutes of Health / National Institute of Diabetes and Digestive and Kidney Diseases RC1DK086450 .
Publisher Copyright:
© 2014 Elsevier Inc.
PY - 2014/10/1
Y1 - 2014/10/1
N2 - BackgroundMethods:Results: Among 10,517 LT recipients, 6.9% (n = 726) required postoperative MCVS, 25.6% of whom required less than 96 hours, 24.2% required 96 hours or longer, and 50.1% received an unspecified duration. Significant predictors of prolonged MCVS included older age, female sex, pretransplant dialysis requirement, and ascites. After multivariate adjustment, MCVS of 96 hours or longer was associated with nearly 3 times the adjusted hazard ratio of mortality (2.95, P <.001), while MCVS less than 96 hours was not significantly associated with mortality (adjusted hazard ratio.88, P =.55)Conclusions: Recognition of LT patients at risk for prolonged MCVS may help to reduce the incidence and consequences of this complication.
AB - BackgroundMethods:Results: Among 10,517 LT recipients, 6.9% (n = 726) required postoperative MCVS, 25.6% of whom required less than 96 hours, 24.2% required 96 hours or longer, and 50.1% received an unspecified duration. Significant predictors of prolonged MCVS included older age, female sex, pretransplant dialysis requirement, and ascites. After multivariate adjustment, MCVS of 96 hours or longer was associated with nearly 3 times the adjusted hazard ratio of mortality (2.95, P <.001), while MCVS less than 96 hours was not significantly associated with mortality (adjusted hazard ratio.88, P =.55)Conclusions: Recognition of LT patients at risk for prolonged MCVS may help to reduce the incidence and consequences of this complication.
KW - Graft failure
KW - Liver transplantation
KW - Mechanical ventilation
KW - Medicare
KW - Mortality
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U2 - 10.1016/j.amjsurg.2014.06.004
DO - 10.1016/j.amjsurg.2014.06.004
M3 - Article
C2 - 25151187
AN - SCOPUS:84908156029
VL - 208
SP - 582
EP - 590
JO - The American Journal of Surgery
JF - The American Journal of Surgery
SN - 0002-9610
IS - 4
ER -