Prognostic impact of mechanical ventilation after liver transplantation: A national database study

Hui Yuan, Janet E. Tuttle-Newhall, Vikram Chawa, Mark A. Schnitzler, Huiling Xiao, David Axelrod, Nino Dzebisashvili, Krista L. Lentine

Research output: Contribution to journalArticlepeer-review

24 Scopus citations

Abstract

Background

Methods:

Results: Among 10,517 LT recipients, 6.9% (n = 726) required postoperative MCVS, 25.6% of whom required less than 96 hours, 24.2% required 96 hours or longer, and 50.1% received an unspecified duration. Significant predictors of prolonged MCVS included older age, female sex, pretransplant dialysis requirement, and ascites. After multivariate adjustment, MCVS of 96 hours or longer was associated with nearly 3 times the adjusted hazard ratio of mortality (2.95, P <.001), while MCVS less than 96 hours was not significantly associated with mortality (adjusted hazard ratio.88, P =.55)

Conclusions: Recognition of LT patients at risk for prolonged MCVS may help to reduce the incidence and consequences of this complication.

Original languageEnglish (US)
Pages (from-to)582-590
Number of pages9
JournalAmerican Journal of Surgery
Volume208
Issue number4
DOIs
StatePublished - Oct 1 2014

Keywords

  • Graft failure
  • Liver transplantation
  • Mechanical ventilation
  • Medicare
  • Mortality

ASJC Scopus subject areas

  • Surgery

Fingerprint

Dive into the research topics of 'Prognostic impact of mechanical ventilation after liver transplantation: A national database study'. Together they form a unique fingerprint.

Cite this