PRODUCTION OF LEUCOCYTE INTERFERON IN VITRO IN CHILDREN WITH RECURRENT RESPIRATORY INFECTIONS

H. Chadda; M. K. Brenner; H. B. Valman; A. D.B. Webster

doi:10.1016/S0140-6736(84)91738-0

PRODUCTION OF LEUCOCYTE INTERFERON IN VITRO IN CHILDREN WITH RECURRENT RESPIRATORY INFECTIONS

H. Chadda, M. K. Brenner, H. B. Valman, A. D.B. Webster

Research output: Contribution to journal › Letter › peer-review

Original language	English (US)
Pages (from-to)	1247
Number of pages	1
Journal	The Lancet
Volume	323
Issue number	8388
DOIs	https://doi.org/10.1016/S0140-6736(84)91738-0
State	Published - Jun 2 1984

ASJC Scopus subject areas

Medicine(all)

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10.1016/S0140-6736(84)91738-0

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@article{6561ed220c5542dcb3006d8f46cacf80,

title = "PRODUCTION OF LEUCOCYTE INTERFERON IN VITRO IN CHILDREN WITH RECURRENT RESPIRATORY INFECTIONS",

author = "H. Chadda and Brenner, {M. K.} and Valman, {H. B.} and Webster, {A. D.B.}",

note = "Funding Information: SIR,-One of us (K. S.) measured the blood pressure (BP) under controlled conditions in about 10 000 schoolchildren 18-22 years ago in Niigata Prefecture, Japan.l We searched out the current address of 245 normotensive subjects previously used as controls (normotensive group) and 202 subjects with raised BP (over 140 mm Hg systolic and/or over 90 mm Hg diastolic) aged between 12 and 15 years at the time of first investigation. We sent them questionnaires by post and collected 186 replies (41 6% of all letters), 103 (42 0% of 245) for normotensive group and 83 (41 - 1 % of 202) for hypertensive group. The frequency of hypertension (over 145 mm Hg systolic BP and/or over 90 mm Hg diastolic) diagnosed by their family doctors was 4-9% (5/103) in the previously normotensive group, which was similar to the expected frequency for a population of this age in Japan, and 20 5% (17/83) in the hypertensive group (p<O 005, chi-squared test). This result suggests that adult hypertension may start in childhood. Essential hypertension in childhood is very labile and potentially reversible.{\textquoteright} We should therefore measure BP every year in all children to identify hypertensives so that we can try to prevent progression to fixed hypertension in adulthood. Supported by a grant-in-aid from the Japanese Scientific Foundation (no 57770618) of the Ministry of Education. * Present address. Renal Untt, Institute of Child Health, London WC1N 1EH.",

year = "1984",

month = jun,

day = "2",

doi = "10.1016/S0140-6736(84)91738-0",

language = "English (US)",

volume = "323",

pages = "1247",

journal = "The Lancet",

issn = "0140-6736",

publisher = "Elsevier Limited",

number = "8388",

}

TY - JOUR

T1 - PRODUCTION OF LEUCOCYTE INTERFERON IN VITRO IN CHILDREN WITH RECURRENT RESPIRATORY INFECTIONS

AU - Chadda, H.

AU - Brenner, M. K.

AU - Valman, H. B.

AU - Webster, A. D.B.

N1 - Funding Information: SIR,-One of us (K. S.) measured the blood pressure (BP) under controlled conditions in about 10 000 schoolchildren 18-22 years ago in Niigata Prefecture, Japan.l We searched out the current address of 245 normotensive subjects previously used as controls (normotensive group) and 202 subjects with raised BP (over 140 mm Hg systolic and/or over 90 mm Hg diastolic) aged between 12 and 15 years at the time of first investigation. We sent them questionnaires by post and collected 186 replies (41 6% of all letters), 103 (42 0% of 245) for normotensive group and 83 (41 - 1 % of 202) for hypertensive group. The frequency of hypertension (over 145 mm Hg systolic BP and/or over 90 mm Hg diastolic) diagnosed by their family doctors was 4-9% (5/103) in the previously normotensive group, which was similar to the expected frequency for a population of this age in Japan, and 20 5% (17/83) in the hypertensive group (p<O 005, chi-squared test). This result suggests that adult hypertension may start in childhood. Essential hypertension in childhood is very labile and potentially reversible.’ We should therefore measure BP every year in all children to identify hypertensives so that we can try to prevent progression to fixed hypertension in adulthood. Supported by a grant-in-aid from the Japanese Scientific Foundation (no 57770618) of the Ministry of Education. * Present address. Renal Untt, Institute of Child Health, London WC1N 1EH.

PY - 1984/6/2

Y1 - 1984/6/2

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U2 - 10.1016/S0140-6736(84)91738-0

DO - 10.1016/S0140-6736(84)91738-0

M3 - Letter

C2 - 6144967

AN - SCOPUS:0021753723

SN - 0140-6736

VL - 323

SP - 1247

JO - The Lancet

JF - The Lancet

IS - 8388

ER -

PRODUCTION OF LEUCOCYTE INTERFERON IN VITRO IN CHILDREN WITH RECURRENT RESPIRATORY INFECTIONS

ASJC Scopus subject areas

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