PRODUCTION OF LEUCOCYTE INTERFERON IN VITRO IN CHILDREN WITH RECURRENT RESPIRATORY INFECTIONS. / Chadda, H.; Brenner, M. K.; Valman, H. B.; Webster, A. D.B.In: The Lancet, Vol. 323, No. 8388, 02.06.1984, p. 1247.
Research output: Contribution to journal › Letter › peer-review
TY - JOUR
T1 - PRODUCTION OF LEUCOCYTE INTERFERON IN VITRO IN CHILDREN WITH RECURRENT RESPIRATORY INFECTIONS
AU - Chadda, H.
AU - Brenner, M. K.
AU - Valman, H. B.
AU - Webster, A. D.B.
N1 - Funding Information: SIR,-One of us (K. S.) measured the blood pressure (BP) under controlled conditions in about 10 000 schoolchildren 18-22 years ago in Niigata Prefecture, Japan.l We searched out the current address of 245 normotensive subjects previously used as controls (normotensive group) and 202 subjects with raised BP (over 140 mm Hg systolic and/or over 90 mm Hg diastolic) aged between 12 and 15 years at the time of first investigation. We sent them questionnaires by post and collected 186 replies (41 6% of all letters), 103 (42 0% of 245) for normotensive group and 83 (41 - 1 % of 202) for hypertensive group. The frequency of hypertension (over 145 mm Hg systolic BP and/or over 90 mm Hg diastolic) diagnosed by their family doctors was 4-9% (5/103) in the previously normotensive group, which was similar to the expected frequency for a population of this age in Japan, and 20 5% (17/83) in the hypertensive group (p<O 005, chi-squared test). This result suggests that adult hypertension may start in childhood. Essential hypertension in childhood is very labile and potentially reversible.’ We should therefore measure BP every year in all children to identify hypertensives so that we can try to prevent progression to fixed hypertension in adulthood. Supported by a grant-in-aid from the Japanese Scientific Foundation (no 57770618) of the Ministry of Education. * Present address. Renal Untt, Institute of Child Health, London WC1N 1EH.
PY - 1984/6/2
Y1 - 1984/6/2
UR - http://www.scopus.com/inward/record.url?scp=0021753723&partnerID=8YFLogxK
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U2 - 10.1016/S0140-6736(84)91738-0
DO - 10.1016/S0140-6736(84)91738-0
M3 - Letter
C2 - 6144967
AN - SCOPUS:0021753723
VL - 323
SP - 1247
JO - The Lancet
JF - The Lancet
SN - 0140-6736
IS - 8388