TY - JOUR
T1 - Prevalence of cardiovascular risk factors in a nationally representative adult population with inflammatory bowel disease without atherosclerotic cardiovascular disease
AU - Agrawal, Tanushree
AU - Acquah, Isaac
AU - Dey, Amit K.
AU - Glassner, Kerri
AU - Abraham, Bincy P.
AU - Blankstein, Ron
AU - Virani, Salim S.
AU - Blaha, Michael J.
AU - Valero-Elizondo, Javier
AU - Mehta, Nehal
AU - Quigley, Eamonn MM
AU - Cainzos-Achirica, Miguel
AU - Nasir, Khurram
N1 - Publisher Copyright:
© 2021
PY - 2021/6
Y1 - 2021/6
N2 - Background and aims: Chronic inflammation is associated with premature atherosclerotic cardiovascular disease (ASCVD). We studied the prevalence of cardiovascular risk factors (CRFs) amongst individuals with IBD who have not developed ASCVD. Methods: Our study population was derived from the 2015 – 2016 National Health Interview Survey. Those with ASCVD (defined as myocardial infarction, angina or stroke) were excluded. The prevalence of CRFs among individuals with IBD was compared with those without IBD. The odds CRFs among adults with IBD was assessed using logistic regression models. Results: In our study population of 60,155 individuals, 786 (1.3%) had IBD. IBD was associated with increased odds hypertension (odds ratio [OR] 1.71, 95% confidence interval [CI] 1.39–2.09), diabetes (OR 1.68, 95% CI 1.22–2.32), hypercholesterolemia (OR 1.62, 95% CI 1.32–2.99) and insufficient physical activity (OR 1.38, 95% CI 1.16–1.66). Conclusion: IBD is associated with higher prevalence of CRFs. Early screening and risk mitigation strategies are warranted.
AB - Background and aims: Chronic inflammation is associated with premature atherosclerotic cardiovascular disease (ASCVD). We studied the prevalence of cardiovascular risk factors (CRFs) amongst individuals with IBD who have not developed ASCVD. Methods: Our study population was derived from the 2015 – 2016 National Health Interview Survey. Those with ASCVD (defined as myocardial infarction, angina or stroke) were excluded. The prevalence of CRFs among individuals with IBD was compared with those without IBD. The odds CRFs among adults with IBD was assessed using logistic regression models. Results: In our study population of 60,155 individuals, 786 (1.3%) had IBD. IBD was associated with increased odds hypertension (odds ratio [OR] 1.71, 95% confidence interval [CI] 1.39–2.09), diabetes (OR 1.68, 95% CI 1.22–2.32), hypercholesterolemia (OR 1.62, 95% CI 1.32–2.99) and insufficient physical activity (OR 1.38, 95% CI 1.16–1.66). Conclusion: IBD is associated with higher prevalence of CRFs. Early screening and risk mitigation strategies are warranted.
KW - Atherosclerosis
KW - Cardiovascular disease
KW - Epidemiology
KW - Inflammatory bowel disease
KW - Risk factors
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U2 - 10.1016/j.ajpc.2021.100171
DO - 10.1016/j.ajpc.2021.100171
M3 - Article
AN - SCOPUS:85118857624
SN - 2666-6677
VL - 6
JO - American Journal of Preventive Cardiology
JF - American Journal of Preventive Cardiology
M1 - 100171
ER -