Presurgical nasoalveolar molding therapy for the treatment of unilateral cleft lip and palate: A preliminary study

Christopher F. Ezzat, Carmen Chavarria, John F. Teichgraeber, Jung Wei Chen, Robin G. Stratmann, Jaime Gateno, James J. Xia

Research output: Contribution to journalArticlepeer-review

78 Scopus citations


Objective: To evaluate the outcome of presurgical nasoalveolar molding (PNAM) therapy in the treatment of patients with nonsyndromic unilateral cleft and palate (UCLP). Design: A prospective study with blinded measurements. Patients: Twelve patients with UCLP treated from 1997 to 2003. Interventions: The starting age for PNAM therapy was 26 days and the average length of the therapy was 110 days. Main Outcome Measures: Measurements of intraoral and extraoral casts were made, and statistical analyses were used to compare the differences between pre- and posttherapy measurements. Results: After PNAM therapy, there was a statistically significant decrease in both intersegment alveolar cleft distance and columellar deviation (p < .05). There was also a statistically significant increase in cleft nostril height, maxillary width, and columellar width (p < .05). Moreover, although there was no statistically significant reduction of the affected nostril width, it demonstrated on average 1.7-mm reduction after PNAM therapy. The length of the time the patient utilized the appliance and postmolding nostril height were found to have a statistically significant positive correlation (p < .05). Conclusions: PNAM therapy decreases intersegment alveolar cleft distance while permitting an increase in posterior maxillary arch width. It also increases nasal symmetry by decreasing columellar deviation, increasing nostril height on the affected side, maintaining bialar width of nose, increasing columellar width, and creating more symmetrical nostril heights and widths. The improvement of the height of the cleft nostril was correlated with the time the appliance was applied.

Original languageEnglish (US)
Pages (from-to)8-12
Number of pages5
JournalCleft Palate-Craniofacial Journal
Issue number1
StatePublished - Jan 1 2007


  • Cleft lip
  • Nasal symmetry
  • Nasoalveolar molding
  • Presurgical orthopedics

ASJC Scopus subject areas

  • Surgery
  • Dentistry(all)


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