Premature coronary artery disease is systematic lupus erythematosus with extensive reocclusion following coronary artery bypass surgery

David J. D'Agate, Spyros Kokolis, Nehad Soloman, Elise Belilos, Steven Carsons, Julia Andrieni, Thomas Argyros, Lynne A. Glasser, George Dangas

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

A 21-year-old woman with a history of systemic lupus erythematosus (SLE) presented to the emergency room with a chief complaint of substernal chest pain and palpitations. She had undergone a four-vessel coronary artery bypass graft operation with separate saphenous vein grafts to the left anterior descending (LAD), obtuse marginal (OM) 1 and 2, and distal right coronary arteries (RCA) 8 months prior to admission. The patient underwent angiography of the coronary vessels, which showed severe diffuse disease with a long, 90% narrowing of the vein graft to the LAD and closed vein grafts to OM1 and OM2. The RCA graft showed mild diffuse disease. An intervention was done in which the LAD was stented twice with subsequent TIMI 3 flow. Advances in medical therapy and a better understanding of the disease have contributed to a dramatic improvement in the long-term survival of patients with SLE. However, despite the overall long-term improvement, coronary artery disease remains a major cause of morbidity and mortality with an incidence of approximately nine-fold greater than would be expected for this population.

Original languageEnglish (US)
Pages (from-to)157-163
Number of pages7
JournalJournal of Invasive Cardiology
Volume15
Issue number3
StatePublished - Mar 1 2003

Keywords

  • Coronary artery disease
  • Systemic lupus erythematosus

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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