TY - JOUR
T1 - Predictors of visual acuity outcomes following vitrectomy for idiopathic macular hole
AU - Amram, Alec L.
AU - Mandviwala, Murtaza M.
AU - Ou, William C.
AU - Wykoff, Charles C.
AU - Shah, Ankoor R.
N1 - Funding Information:
Originally submitted July 29, 2017. Revision received October 10, 2017. Accepted for publication November 2, 2017. Dr. Wykoff has received grants and personal fees from Alcon Laboratories, Allergan, Clearside Biomedical, Genentech, Iconic Therapeutics, and Regen-eron; personal fees from Alimera Sciences, Alnylam Pharmaceuticals, Bayer, D.O.R.C., ONL Therapeutics, Thrombogenics, and Valeant; and grants from Allegro, Apellis, Aura, NEI, NIH, Novartis, OHR Pharmaceuticals, Ophthotech, pSivida, Roche, Santen, SciFluor Life Sciences, and Tyrogenex outside the submitted work. The remaining authors report no relevant financial disclosures. Address correspondence to Ankoor R. Shah, MD, Retina Consultants of Houston, 6560 Fannin St., Suite 750, Houston, TX 77030; email: [email protected]. doi: 10.3928/23258160-20180803-03
Publisher Copyright:
© 2018 Slack Incorporated. All rights reserved.
PY - 2018/8/1
Y1 - 2018/8/1
N2 - BACKGROUND AND OBJECTIVE: To investigate predictors of visual outcomes in patients who underwent vitrectomy for full-thickness macular hole (FTMH) with at least 1 year of follow-up. PATIENTS AND METHODS: Retrospective, noncom-parative, consecutive case series of 132 eyes of 122 patients who underwent surgical repair of idiopathic FTMH with at least 1 year of follow-up. Predictors of visual acuity (VA) outcomes were analyzed using linear regression. RESULTS: Mean follow-up time was 22.2 months. Twenty-three eyes (17.4%) had age-related macular degeneration (AMD), of which 17 (73.9%) cases were mild and nonexudative. At final follow-up, poor preoperative VA (P < .001), perioperative complications (P < .001), AMD (P < .001), and delay from preoperative evaluation to surgery (P = .037) were significant predictors of final VA. In multiple regression, these variables remained significant (P < .001, P = .011, P < .001, and P = .002, respectively). CONCLUSION: Poor preoperative VA, perioperative complications, AMD, and delay to surgery were significant predictors of final VA following FTMH repair.
AB - BACKGROUND AND OBJECTIVE: To investigate predictors of visual outcomes in patients who underwent vitrectomy for full-thickness macular hole (FTMH) with at least 1 year of follow-up. PATIENTS AND METHODS: Retrospective, noncom-parative, consecutive case series of 132 eyes of 122 patients who underwent surgical repair of idiopathic FTMH with at least 1 year of follow-up. Predictors of visual acuity (VA) outcomes were analyzed using linear regression. RESULTS: Mean follow-up time was 22.2 months. Twenty-three eyes (17.4%) had age-related macular degeneration (AMD), of which 17 (73.9%) cases were mild and nonexudative. At final follow-up, poor preoperative VA (P < .001), perioperative complications (P < .001), AMD (P < .001), and delay from preoperative evaluation to surgery (P = .037) were significant predictors of final VA. In multiple regression, these variables remained significant (P < .001, P = .011, P < .001, and P = .002, respectively). CONCLUSION: Poor preoperative VA, perioperative complications, AMD, and delay to surgery were significant predictors of final VA following FTMH repair.
UR - https://www.scopus.com/pages/publications/85052994564
UR - https://www.scopus.com/inward/citedby.url?scp=85052994564&partnerID=8YFLogxK
U2 - 10.3928/23258160-20180803-03
DO - 10.3928/23258160-20180803-03
M3 - Article
C2 - 30114300
AN - SCOPUS:85052994564
SN - 2325-8160
VL - 49
SP - 566
EP - 570
JO - Ophthalmic Surgery Lasers and Imaging Retina
JF - Ophthalmic Surgery Lasers and Imaging Retina
IS - 8
ER -