Prediabetes: Why Should We Care?

Ashkan Zand, Karim Ibrahim, Bhargavi Patham

Research output: Contribution to journalReview articlepeer-review

51 Scopus citations


A clear link between cardiovascular disease and prediabetes has emerged over the past few years. Recent studies have shown that patients with prediabetes can suffer from coronary artery disease and diastolic heart failure even before progressing to overt diabetes. With this knowledge, physicians must identify prediabetes and take appropriate measures to optimize glycemic control. The pathophysiological defect seen in prediabetes can be managed with lifestyle modifications; thus, it is essential that physicians have a clear understanding of the current recommendations regarding diet and exercise. This review outlines the complications associated with prediabetes, presents an overview of the available pharmacological and surgical therapies that are effective in treating it, and provides a stepwise, multipronged approach for management.

Original languageEnglish (US)
Pages (from-to)289-297
Number of pages9
JournalMethodist DeBakey cardiovascular journal
Issue number4
StatePublished - Oct 1 2018


  • diabetes prevention
  • impaired fasting glucose
  • impaired glucose tolerance
  • management of prediabetes
  • prediabetes

ASJC Scopus subject areas

  • Medicine(all)


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