Precocious 'feminization' of rat liver enzymes in the presence of ectopic pituitary tissue

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5 Scopus citations

Abstract

The presence of ectopic pituitary tissue (derived from an adult rat) in prepubertal male and female rats caus ed the immature, masculine-type hepatic steroid metabolism to develop into female-type metabolism. It is concluded that the hypothalamus-pituitary system controls the ontogenesis of sex-dependent steroid metabolism in rat liver.

Original languageEnglish (US)
Pages (from-to)187-191
Number of pages5
JournalJournal of Endocrinology
Volume76
Issue number2
DOIs
StatePublished - 1978

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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