Precision Attachment of Individual F1-ATPaSe Biomolecular Motors on Nanofabricated Substrates

G. D. Bachand, R. K. Soong, H. P. Neves, A. Olkhovets, Harold G. Craighead, C. D. Montemagno

Research output: Contribution to journalArticle

40 Scopus citations

Abstract

The ability to precisely position and orient biological molecules on engineered substrates is an enabling technology critical to the long-term goal of integrating biomolecular motors with nano-electro-mechanical systems. Electron beam lithography and nanoimprinting techniques were used to produce arrays of nickel dots (50-200 nm diameter). Analysis using fluorescence (of microspheres attached to the γ subunit) and atomic force microscopy of these arrays demonstrated precise positioning, spacing, and orientation of individual F1-ATPase molecules.

Original languageEnglish (US)
Pages (from-to)42-44
Number of pages3
JournalNano Letters
Volume1
Issue number1
DOIs
StatePublished - Jan 1 2001

ASJC Scopus subject areas

  • Bioengineering
  • Chemistry(all)
  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanical Engineering

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