TY - GEN
T1 - Precise control of trapping/release of individual label-free droplets in comb-shaped microfluidic chip using magnetic repulsion
AU - Zhang, Kai
AU - Liang, Qionglin
AU - Wang, Yiming
AU - Luo, Guoan
PY - 2011
Y1 - 2011
N2 - An improved magnetic repulsion-actuated method is presented for precise control of trapping and release of individual pi-coliter droplets in comb-shaped microfluidic chip. The initial distance between droplets and microwells are same and maximized by forcing droplets to flow along a straight microchannel wall, making single droplet easier to be selected and trapped into designated microwell. Trapped droplets are isolated from ferrofluid by utilizing the effect of laminar flow between ferrofluid and mineral oil, effectively reducing undesired interference from magnetic repulsion to adjacent droplets. Moreover, ferrofluid can be completely displaced by mineral oil for eliminating adverse effects from surfactants.
AB - An improved magnetic repulsion-actuated method is presented for precise control of trapping and release of individual pi-coliter droplets in comb-shaped microfluidic chip. The initial distance between droplets and microwells are same and maximized by forcing droplets to flow along a straight microchannel wall, making single droplet easier to be selected and trapped into designated microwell. Trapped droplets are isolated from ferrofluid by utilizing the effect of laminar flow between ferrofluid and mineral oil, effectively reducing undesired interference from magnetic repulsion to adjacent droplets. Moreover, ferrofluid can be completely displaced by mineral oil for eliminating adverse effects from surfactants.
UR - https://www.scopus.com/pages/publications/84883796205
UR - https://www.scopus.com/inward/citedby.url?scp=84883796205&partnerID=8YFLogxK
M3 - Conference contribution
BT - 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences
ER -