Precise control of trapping/release of individual label-free droplets in comb-shaped microfluidic chip using magnetic repulsion

Kai Zhang, Qionglin Liang, Yiming Wang, Guoan Luo

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

An improved magnetic repulsion-actuated method is presented for precise control of trapping and release of individual pi-coliter droplets in comb-shaped microfluidic chip. The initial distance between droplets and microwells are same and maximized by forcing droplets to flow along a straight microchannel wall, making single droplet easier to be selected and trapped into designated microwell. Trapped droplets are isolated from ferrofluid by utilizing the effect of laminar flow between ferrofluid and mineral oil, effectively reducing undesired interference from magnetic repulsion to adjacent droplets. Moreover, ferrofluid can be completely displaced by mineral oil for eliminating adverse effects from surfactants.
Original languageEnglish (US)
Title of host publication15th International Conference on Miniaturized Systems for Chemistry and Life Sciences
StatePublished - 2011

Fingerprint Dive into the research topics of 'Precise control of trapping/release of individual label-free droplets in comb-shaped microfluidic chip using magnetic repulsion'. Together they form a unique fingerprint.

Cite this