Practical applications of immunohistochemistry in the diagnosis of genitourinary tumors

Xiuli Xiao, Rong Hu, Fang Ming Deng, Steven S. Shen, Ximing J. Yang, Chin Lee Wu

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

Context.-Pathologic diagnosis of tumors in the genitourinary system can be challenging based on morphology alone, particularly when diagnostic material is limited, such as in core biopsies. Immunohistochemical stain can be a useful tool to aid in the diagnosis. Objective.-To provide an update on practical applications and interpretation of immunohistochemical stains in the diagnosis of tumors in prostate, kidney, bladder, and testis. We particularly focus on difficult differential diagnoses, providing our insights in frequently encountered challenging situations. Commonly used immunohistochemical panels are discussed. Data Sources.-Review of literature and our own experience. Conclusion.-Immunohistochemical stain is a valuable tool in the diagnosis of genitourinary tumors when appropriately used.

Original languageEnglish (US)
Pages (from-to)1181-1194
Number of pages14
JournalArchives of Pathology and Laboratory Medicine
Volume141
Issue number9
DOIs
StatePublished - Sep 2017

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology

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