Potential False-Positive FDG PET Imaging Caused by Subcutaneous Radiotracer Infiltration

Stephen Chiang; Alan Rebenstock; Liang Guan; Jason Burns; Abass Alavi; Hongming Zhuang

doi:10.1097/01.rlu.0000082677.96653.22

Potential False-Positive FDG PET Imaging Caused by Subcutaneous Radiotracer Infiltration

Stephen Chiang, Alan Rebenstock, Liang Guan, Jason Burns, Abass Alavi, Hongming Zhuang

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

Whole-body fluorine-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) scanning has been useful in the management of a variety of malignancies with high accuracy. However, numerous nonmalignant lesions can also result in increased FDG accumulation and consequently may cause potential false-positive interpretation if the causes are not recognized. A single focus of FDG accumulation in the axilla can often easily be attributed to tracer infiltration when the injection was on the same side. However, multiple foci of FDG uptake can be similar to malignant lesions. A case is presented in which the follow-up study clarified the nature of multifocal increased FDG uptake in the axilla.

Original language	English (US)
Pages (from-to)	786-788
Number of pages	3
Journal	Clinical Nuclear Medicine
Volume	28
Issue number	9
DOIs	https://doi.org/10.1097/01.rlu.0000082677.96653.22
State	Published - Sep 1 2003

Keywords

False positive
FDG PET
Lymphoma
Tracer extravasation

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Radiological and Ultrasound Technology

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10.1097/01.rlu.0000082677.96653.22

Cite this

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title = "Potential False-Positive FDG PET Imaging Caused by Subcutaneous Radiotracer Infiltration",

abstract = "Whole-body fluorine-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) scanning has been useful in the management of a variety of malignancies with high accuracy. However, numerous nonmalignant lesions can also result in increased FDG accumulation and consequently may cause potential false-positive interpretation if the causes are not recognized. A single focus of FDG accumulation in the axilla can often easily be attributed to tracer infiltration when the injection was on the same side. However, multiple foci of FDG uptake can be similar to malignant lesions. A case is presented in which the follow-up study clarified the nature of multifocal increased FDG uptake in the axilla.",

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AU - Chiang, Stephen

AU - Rebenstock, Alan

AU - Guan, Liang

AU - Burns, Jason

AU - Alavi, Abass

AU - Zhuang, Hongming

PY - 2003/9/1

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N2 - Whole-body fluorine-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) scanning has been useful in the management of a variety of malignancies with high accuracy. However, numerous nonmalignant lesions can also result in increased FDG accumulation and consequently may cause potential false-positive interpretation if the causes are not recognized. A single focus of FDG accumulation in the axilla can often easily be attributed to tracer infiltration when the injection was on the same side. However, multiple foci of FDG uptake can be similar to malignant lesions. A case is presented in which the follow-up study clarified the nature of multifocal increased FDG uptake in the axilla.

AB - Whole-body fluorine-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) scanning has been useful in the management of a variety of malignancies with high accuracy. However, numerous nonmalignant lesions can also result in increased FDG accumulation and consequently may cause potential false-positive interpretation if the causes are not recognized. A single focus of FDG accumulation in the axilla can often easily be attributed to tracer infiltration when the injection was on the same side. However, multiple foci of FDG uptake can be similar to malignant lesions. A case is presented in which the follow-up study clarified the nature of multifocal increased FDG uptake in the axilla.

KW - False positive

KW - FDG PET

KW - Lymphoma

KW - Tracer extravasation

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Potential False-Positive FDG PET Imaging Caused by Subcutaneous Radiotracer Infiltration

Abstract

Keywords

ASJC Scopus subject areas

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