Potency of combined estrogenic pesticides: Synergy between synthetic oestrogens?

K. Ramamoorthy, F. Wang, I. C. Chen, S. Safe, J. D. Norris, D. P. McDonnell, K. W. Gaido, W. P. Bocchinfuso, K. S. Korach, J. Ashby, P. A. Lefevre, J. Odum, C. A. Harris, E. J. Routledge, J. P. Sumpter

Research output: Contribution to journalReview articlepeer-review


These studies each show that certain binary mixtures of weak, environmental estrogens act additively. The results were obtained by testing mixtures of these compounds in a variety of estrogen assays. These studies were prompted by a now retracted report that such binary mixtures act synergistically, not simply additively. The structures of the compounds used in these studies are shown below.

Original languageEnglish (US)
Pages (from-to)306-308
Number of pages3
Issue number4
StatePublished - Apr 1998

ASJC Scopus subject areas

  • Chemistry(all)
  • Biochemistry
  • Molecular Biology


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