Posttraumatic stress disorder's dysphoria dimension and relations with generalized anxiety disorder symptoms

Tory A. Durham, Jon D. Elhai, Thomas H. Fine, Marijo Tamburrino, Gregory Cohen, Edwin Shirley, Philip K. Chan, Israel Liberzon, Sandro Galea, Joseph R. Calabrese

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


The present study investigated symptom relations between two highly comorbid disorders - posttraumatic stress disorder (PTSD) and generalized anxiety disorder (GAD) - by exploring their underlying dimensions. Based on theory and prior empirical research it was expected that the dysphoria factor of PTSD would be more highly related to GAD. As part of a longitudinal project of mental health among Ohio National Guard Soldiers, 1266 subjects were administered the Posttraumatic Stress Disorder Checklist (PCL) and Generalized Anxiety Disorder-7 scale (GAD-7). Confirmatory factor analyses (CFAs) were conducted to examine two models of PTSD and to determine which PTSD factors were more related to the GAD factor. The results indicate that the GAD factor was significantly more highly correlated with PTSD's dysphoria factor than with all other PTSD factors, including PTSD's reexperiencing factor, avoidance factor, and hyperarousal factor. Results indicate GAD was not significantly more highly correlated with numbing than most other factors of PTSD. The results are consistent with prior research. Implications of the results are discussed in regards to PTSD in DSM-5, comorbidity and diagnostic specificity.

Original languageEnglish (US)
Pages (from-to)150-155
Number of pages6
JournalPsychiatry Research
Issue number1
StatePublished - Jul 30 2015


  • Comorbidity
  • Confirmatory factor analysis
  • Dysphoria
  • Generalized anxiety disorder
  • Posttraumatic stress disorder

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry


Dive into the research topics of 'Posttraumatic stress disorder's dysphoria dimension and relations with generalized anxiety disorder symptoms'. Together they form a unique fingerprint.

Cite this