Positron Emission Tomography-CT Imaging in Guiding Musculoskeletal Biopsy

Paul J. O'Sullivan, Eric M. Rohren, John E. Madewell

Research output: Contribution to journalReview articlepeer-review

20 Scopus citations


Positron emission tomography (PET)-computed tomography (CT) is a useful device in identifying musculoskeletal lesions that require biopsy. It can be used to localize the primary lesion, identify a site to biopsy, and evaluate metastatic lesions that require follow-up biopsies. Not all malignant tumors have hypermetabolic activity, and there are many benign lesions and physiologic processes that do have increased F-18 fluorodeoxyglucose uptake. Knowledge of these issues is important when reviewing PET-CT and directing subsequent musculoskeletal biopsies.

Original languageEnglish (US)
Pages (from-to)475-486
Number of pages12
JournalRadiologic Clinics of North America
Issue number3
StatePublished - May 2008


  • Biopsy
  • Musculoskeletal
  • PET-CT

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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