Porous phosphate-gelatine composite as bone graft with drug delivery function

A. Tampieri, G. Celotti, E. Landi, M. Montevecchi, N. Roveri, A. Bigi, S. Panzavolta, M. C. Sidoti

Research output: Contribution to journalArticle

24 Scopus citations

Abstract

The design and synthesis of porous phosphate-gelatine composite implant which mimicks the structure of natural bone and has drug delivery function is proposed. Gelatine reproducing the proteinaceous part of bone was cross-linked in order to modulate its solubility in the physiologic fluids. The kinetic of gelatine release from ceramic matrix was also evaluated as model of the release of any therapeutic compound which can be loaded into gelatine.

Original languageEnglish (US)
Pages (from-to)623-627
Number of pages5
JournalJournal of Materials Science: Materials in Medicine
Volume14
Issue number7
DOIs
StatePublished - Jul 1 2003

ASJC Scopus subject areas

  • Biophysics
  • Bioengineering
  • Biomaterials
  • Biomedical Engineering

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