Polymorphisms in the estrogen receptor beta gene and risk of breast cancer: No association

Asta Försti, Chunyan Zhao, Elisabeth Israelsson, Karin Dahlman-Wright, Jan Åke Gustafsson, Kari Hemminki

Research output: Contribution to journalArticle

40 Scopus citations

Abstract

Polymorphisms in the estrogen receptor beta (ERβ) gene may influence the cellular growth regulating effects of estradiol. In this first association study about breast cancer risk and polymorphisms in the ERβ gene we have screened 219 Finnish sporadic breast cancer cases and 248 ethnically matched male controls. No difference in the allele distribution of the six studied polymorphisms was found between the breast cancer and control groups.

Original languageEnglish (US)
Pages (from-to)409-413
Number of pages5
JournalBreast Cancer Research and Treatment
Volume79
Issue number3
DOIs
StatePublished - Jun 2003

Keywords

  • Breast cancer
  • Estrogen receptor beta
  • Polymorphism

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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