Poisonings and overdoses in the intensive care unit: General and specific management issues

Janice L. Zimmerman

Research output: Contribution to journalReview articlepeer-review

82 Scopus citations


Objective: To provide current information on general and specific Interventions for overdoses likely to require intensive care. Design: Review of literature relevant to selected interventions for general management of overdoses and specific poisons. Results: The benefit of interventions to decrease absorption or enhance elimination of toxins is limited to a relatively small number of specific agents. Antidotes and certain interventions may be helpful in preventing or treating toxicity in specific poisonings when used appropriately. Intensive supportive care is also necessary to achieve good outcomes. Conclusion: Knowledge of the indications and limitations of current interventions for poisonings and overdoses is important for care of the critically ill poisoned patient.

Original languageEnglish (US)
Pages (from-to)2794-2801
Number of pages8
JournalCritical Care Medicine
Issue number12
StatePublished - Dec 1 2003


  • β-blockers
  • Acetaminophen
  • Alternative medicines
  • Calcium channel blockers
  • Carbon monoxide salicylates
  • Cocaine
  • Critical care
  • Cyclic antidepressants
  • Ethylene glycol
  • Lithium
  • Methanol
  • Overdose
  • Poisoning

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine


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