Point-of-care technologies for molecular diagnostics using a drop of blood

Yujun Song; Yu Yen Huang; Xuewu Liu; Xiaojing Zhang; Mauro Ferrari; Lidong Qin

doi:10.1016/j.tibtech.2014.01.003

Point-of-care technologies for molecular diagnostics using a drop of blood

Yujun Song, Yu Yen Huang, Xuewu Liu, Xiaojing Zhang, Mauro Ferrari, Lidong Qin

Research output: Contribution to journal › Review article › peer-review

210 Scopus citations

Abstract

Molecular diagnostics is crucial for prevention, identification, and treatment of disease. Traditional technologies for molecular diagnostics using blood are limited to laboratory use because they rely on sample purification and sophisticated instruments, are labor and time intensive, expensive, and require highly trained operators. This review discusses the frontiers of point-of-care (POC) diagnostic technologies using a drop of blood obtained from a finger prick. These technologies, including emerging biotechnologies, nanotechnologies, and microfluidics, hold the potential for rapid, accurate, and inexpensive disease diagnostics.

Original language	English (US)
Pages (from-to)	132-139
Number of pages	8
Journal	Trends in Biotechnology
Volume	32
Issue number	3
DOIs	https://doi.org/10.1016/j.tibtech.2014.01.003
State	Published - Mar 2014

Keywords

Biomolecules
Circulating tumor cells
Molecular diagnostics
Nucleic acids
Point-of-care diagnostics
Proteins

ASJC Scopus subject areas

Biotechnology
Bioengineering

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10.1016/j.tibtech.2014.01.003

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title = "Point-of-care technologies for molecular diagnostics using a drop of blood",

abstract = "Molecular diagnostics is crucial for prevention, identification, and treatment of disease. Traditional technologies for molecular diagnostics using blood are limited to laboratory use because they rely on sample purification and sophisticated instruments, are labor and time intensive, expensive, and require highly trained operators. This review discusses the frontiers of point-of-care (POC) diagnostic technologies using a drop of blood obtained from a finger prick. These technologies, including emerging biotechnologies, nanotechnologies, and microfluidics, hold the potential for rapid, accurate, and inexpensive disease diagnostics.",

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author = "Yujun Song and Huang, \{Yu Yen\} and Xuewu Liu and Xiaojing Zhang and Mauro Ferrari and Lidong Qin",

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AU - Song, Yujun

AU - Huang, Yu Yen

AU - Liu, Xuewu

AU - Zhang, Xiaojing

AU - Ferrari, Mauro

AU - Qin, Lidong

PY - 2014/3

Y1 - 2014/3

N2 - Molecular diagnostics is crucial for prevention, identification, and treatment of disease. Traditional technologies for molecular diagnostics using blood are limited to laboratory use because they rely on sample purification and sophisticated instruments, are labor and time intensive, expensive, and require highly trained operators. This review discusses the frontiers of point-of-care (POC) diagnostic technologies using a drop of blood obtained from a finger prick. These technologies, including emerging biotechnologies, nanotechnologies, and microfluidics, hold the potential for rapid, accurate, and inexpensive disease diagnostics.

AB - Molecular diagnostics is crucial for prevention, identification, and treatment of disease. Traditional technologies for molecular diagnostics using blood are limited to laboratory use because they rely on sample purification and sophisticated instruments, are labor and time intensive, expensive, and require highly trained operators. This review discusses the frontiers of point-of-care (POC) diagnostic technologies using a drop of blood obtained from a finger prick. These technologies, including emerging biotechnologies, nanotechnologies, and microfluidics, hold the potential for rapid, accurate, and inexpensive disease diagnostics.

KW - Biomolecules

KW - Circulating tumor cells

KW - Molecular diagnostics

KW - Nucleic acids

KW - Point-of-care diagnostics

KW - Proteins

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Point-of-care technologies for molecular diagnostics using a drop of blood

Abstract

Keywords

ASJC Scopus subject areas

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