Point-of-care technologies for molecular diagnostics using a drop of blood

Yujun Song, Yu Yen Huang, Xuewu Liu, Xiaojing Zhang, Mauro Ferrari, Lidong Qin

Research output: Contribution to journalReview articlepeer-review

169 Scopus citations


Molecular diagnostics is crucial for prevention, identification, and treatment of disease. Traditional technologies for molecular diagnostics using blood are limited to laboratory use because they rely on sample purification and sophisticated instruments, are labor and time intensive, expensive, and require highly trained operators. This review discusses the frontiers of point-of-care (POC) diagnostic technologies using a drop of blood obtained from a finger prick. These technologies, including emerging biotechnologies, nanotechnologies, and microfluidics, hold the potential for rapid, accurate, and inexpensive disease diagnostics.

Original languageEnglish (US)
Pages (from-to)132-139
Number of pages8
JournalTrends in Biotechnology
Issue number3
StatePublished - Mar 2014


  • Biomolecules
  • Circulating tumor cells
  • Molecular diagnostics
  • Nucleic acids
  • Point-of-care diagnostics
  • Proteins

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering


Dive into the research topics of 'Point-of-care technologies for molecular diagnostics using a drop of blood'. Together they form a unique fingerprint.

Cite this