Ploidy studies by image analysis on fine needle aspirates of the breast

S. R. Taylor; S. Zachariah; S. Chakraborty; J. Overstreet; I. Ramzy; D. R. Mody

Ploidy studies by image analysis on fine needle aspirates of the breast

S. R. Taylor, S. Zachariah, S. Chakraborty, J. Overstreet, I. Ramzy, D. R. Mody

Research output: Contribution to journal › Article › peer-review

Abstract

Quantitative DNA analysis was performed on preoperative fine needle aspirates of 12 breast cancers and 1 benign lesion using the Cell Analysis Systems (CAS) Model 200 image analysis system. The smears were prepared on CAS slides, routinely processed for Papanicolaou staining, and then destained and restained with Feulgen stain after cytologic evaluation. Four cases were DNA diploid, 3 were tetraploid, 1 was diploid/tetraploid, and 5 were aneuploid. When compared to analysis of samples from the resected tumor, both DNA index and S-phase fraction were constant.

Original language	English (US)
Pages (from-to)	923-928
Number of pages	6
Journal	Acta Cytologica
Volume	37
Issue number	6
State	Published - 1993

ASJC Scopus subject areas

Pathology and Forensic Medicine
Histology

Cite this

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AU - Taylor, S. R.

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AU - Overstreet, J.

AU - Ramzy, I.

AU - Mody, D. R.

PY - 1993

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AB - Quantitative DNA analysis was performed on preoperative fine needle aspirates of 12 breast cancers and 1 benign lesion using the Cell Analysis Systems (CAS) Model 200 image analysis system. The smears were prepared on CAS slides, routinely processed for Papanicolaou staining, and then destained and restained with Feulgen stain after cytologic evaluation. Four cases were DNA diploid, 3 were tetraploid, 1 was diploid/tetraploid, and 5 were aneuploid. When compared to analysis of samples from the resected tumor, both DNA index and S-phase fraction were constant.

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Ploidy studies by image analysis on fine needle aspirates of the breast

Abstract

ASJC Scopus subject areas

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