PLK1 and β-TrCP-dependent ubiquitination and degradation of Rap1GAP controls cell proliferation

Agriculture & Biology

• ubiquitination 100%
• mitosis 76%
• cell proliferation 71%
• GTPase-activating proteins 57%
• tumor suppressor genes 56%
• degradation 48%
• proteasome endopeptidase complex 46%
• guanosinetriphosphatase 45%
• ubiquitin 43%
• ligases 38%
• proteolysis 38%
• cell cycle 35%
• phosphotransferases (kinases) 34%
• neoplasms 30%
• hydrolysis 29%

Medicine & Life Sciences

• Ubiquitination 86%
• Mitosis 78%
• GTPase-Activating Proteins 53%
• Cell Proliferation 52%
• GTP Phosphohydrolases 45%
• Ligases 43%
• Guanosine Triphosphate 42%
• Proteasome Endopeptidase Complex 41%
• Ubiquitin 39%
• Tumor Suppressor Genes 39%
• Proteolysis 37%
• Hydrolysis 36%
• Cell Cycle 31%
• Phosphotransferases 30%
• Down-Regulation 27%
• Neoplasms 12%

Chemistry

• Protein Hydrolysis 86%
• Hydrolysis 49%
• Protein 32%