Skip to main navigation Skip to search Skip to main content

Pleomorphic Adenoma-Like Tumor in the Kidney: Case Report of a Rare Mixed Tumor

Eric Y. Zhang, Haneen T. Salah, Danice K. Torman, Mukul K. Divatia, Haijun Zhou

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Pleomorphic adenoma is the most common salivary gland tumor and is notably able to metastasize while displaying a benign-appearing morphological appearance, greatly resembling that of the primary tumor. Case Report: Here, we report a case of a 66-year-old male who presented with a 7-month history of a left upper renal mass. Microscopic examination revealed characteristics typical of pleomorphic adenoma, including chondromyxoid stroma and benign ductal and tubular cells. Consequently, a diagnosis of benign mixed tumor resembling a metastasizing pleomorphic adenoma (MPA) to the kidney was made. Conclusions: We report a rare instance of a tumor resembling pleomorphic adenoma with metastasis to the kidney, the 13th reported case of kidney metastasis in the literature. This case is additionally the 2nd case with metastases to the kidney and no known primary salivary gland tumor. We believe that this entity is most consistent with the histopathological findings reported in our case, despite the lack of a patient history of primary salivary gland tumor. We subsequently compare patient outcomes across all known cases of benign MPA to the kidney or PA-like tumors in the kidney with patient outcomes described in a 2015 study that analyzed all cases of MPA in the literature.

Original languageEnglish (US)
Article number8959506
JournalCase Reports in Nephrology
Volume2025
Issue number1
DOIs
StatePublished - 2025

Keywords

  • adenoma
  • kidney neoplasms
  • malignant
  • mixed tumor
  • neoplasm metastasis
  • pleomorphic
  • salivary gland neoplasm

ASJC Scopus subject areas

  • Nephrology

Fingerprint

Dive into the research topics of 'Pleomorphic Adenoma-Like Tumor in the Kidney: Case Report of a Rare Mixed Tumor'. Together they form a unique fingerprint.

Cite this