TY - JOUR
T1 - Piribedil Test in Migraine
T2 - Neruoendocrinological Aspects
AU - Bussone, G.
AU - Lamperti, E.
AU - LaMantia, L.
AU - Vescovi, A.
AU - Peccarisi, C.
AU - Boiardi, A.
N1 - Copyright:
Copyright 2016 Elsevier B.V., All rights reserved.
PY - 1986/10
Y1 - 1986/10
N2 - SYNOPSIS Piribedil is a direct central dopamine receptor agonist drug, clinically useful in the diagnosis of migraine. It mayalso be used in the study of migraine pathogenesis, through evaluating dopaminergic “tone”.The observed effects of Piribedil on GH and PRL release, in this study, indicate the existence of dopaminereceptor hypersensitivity in migraine patients. Furthermore our data suggest also the involvement ofnoradrenergic systems in migraine pathogenesis. Estrogen levels do not influence these neuroendocrinologicalresponses to Piribedil, even though the Piribedil test in these female migraine patients was clinically positive (andtherefore diagnostically useful) only during the perimenstrual phase.
AB - SYNOPSIS Piribedil is a direct central dopamine receptor agonist drug, clinically useful in the diagnosis of migraine. It mayalso be used in the study of migraine pathogenesis, through evaluating dopaminergic “tone”.The observed effects of Piribedil on GH and PRL release, in this study, indicate the existence of dopaminereceptor hypersensitivity in migraine patients. Furthermore our data suggest also the involvement ofnoradrenergic systems in migraine pathogenesis. Estrogen levels do not influence these neuroendocrinologicalresponses to Piribedil, even though the Piribedil test in these female migraine patients was clinically positive (andtherefore diagnostically useful) only during the perimenstrual phase.
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U2 - 10.1111/j.1526-4610.1986.hed2609482.x
DO - 10.1111/j.1526-4610.1986.hed2609482.x
M3 - Article
C2 - 3781836
AN - SCOPUS:0022802863
SN - 0017-8748
VL - 26
SP - 482
EP - 485
JO - Headache: The Journal of Head and Face Pain
JF - Headache: The Journal of Head and Face Pain
IS - 9
ER -