Pim-2 upregulation: Biological implications associated with disease progression and perinueral invasion in prostate cancer

Keyphrases

• Prostate Cancer 100%
• Disease Progression 100%
• PIM2 100%
• Biological Consequences 100%
• Small Interfering RNA (siRNA) 25%
• Experimental Sample 25%
• Apoptosis 16%
• Perineural Invasion 16%
• Silencer 16%
• Means of Control 16%
• Sample Mean 16%
• High Risk 8%
• Western Blot 8%
• MRNA Level 8%
• Nerve 8%
• RNA Interference 8%
• Novel Therapeutics 8%
• Ki-67 8%
• In Vitro Model 8%
• Prognostic Factors 8%
• Ki-67 Index 8%
• Apoptotic Pathway 8%
• Microarray 8%
• Total RNA 8%
• TUNEL 8%
• Radical Prostatectomy 8%
• Two-level 8%
• Biochemical Recurrence 8%
• Pro-survival 8%
• Serine-threonine Kinase 8%
• GAPDH 8%
• Quantitative RT-PCR 8%
• Nuclear Translocation 8%
• Aggressive Phenotype 8%
• DU145 8%
• Anti-apoptotic Pathways 8%
• Inhibitor of Apoptosis Proteins 8%
• Pro-survival Genes 8%

Biochemistry, Genetics and Molecular Biology

• Upregulation 100%
• Small Interfering RNA 100%
• Programmed Cell Death 66%
• Ki-67 66%
• Messenger RNA 33%
• RNA 33%
• Western Blot 33%
• Transfection 33%
• Quantitative Reverse Transcription Polymerase Chain Reaction 33%
• Serine 33%
• Threonine 33%
• Phosphotransferase 33%
• Kinase 33%
• RNA Interference 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Prostate Cancer 100%
• Disease Exacerbation 100%
• Small Interfering RNA 60%
• Perineural Invasion 40%
• Messenger RNA 20%
• Western Blot 20%
• Antiapoptotic 20%
• Biochemical Recurrence 20%
• Protein Serine Threonine Kinase 20%