Physiological regulation of uteroglobin/CCSP expression

Albert Chang, Patricia Ramsay, Bihong Zhao, Moon Park, Susan Magdaleno, Michael J. Reardon, Stephen Welty, Francesco J. Demayo

Research output: Contribution to journalArticle

20 Scopus citations

Abstract

Uteroglobin/CCSP is expressed specifically in the Clara cells. This allows the gene to be used as a marker to identify the elements regulating the physiologic and cell-specific expression of this gene. The regulation of UG/CCSP by IFN-γ was shown to be at the level of the proximal promoter by the upregulation of HNF3β. This has allowed the determination of the factors responsible for the expression of UG/CCSP.

Original languageEnglish (US)
Pages (from-to)181-192
Number of pages12
JournalAnnals of the New York Academy of Sciences
Volume923
DOIs
StatePublished - 2000

ASJC Scopus subject areas

  • Neuroscience(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • History and Philosophy of Science

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