Physiological Concepts of Cardiogenic Shock Using Pressure-Volume Loop Simulations: A Case-Based Review

Benjamin C. Salgado, Arvind Bhimaraj

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations


Cardiogenic shock (CS) is a complex syndrome of end-organ hypoperfusion that requires timely and thorough decision making. While many pathophysiologic and technical principles have been delineated in this issue, the purpose of this case-based report is to reflect upon some of these principles in the context of real-life scenarios. Given the obvious lacuna of evidence-based recommendations in CS, the authors provide a rationale for their decision-making process. The first case is a young post-heart-transplant patient with graft failure who was in a state of biventricular failure and restrictive physiology and required acute mechanical circulatory support (MCS). The second case is a patient who suffered a mechanical complication after experiencing an acute myocardial infarction that required MCS.

Original languageEnglish (US)
Pages (from-to)43-49
Number of pages7
JournalMethodist DeBakey cardiovascular journal
Issue number1
StatePublished - Jan 1 2020


  • cardiogenic shock
  • heart failure
  • mechanical support devices
  • pressure volume loop physiology
  • Graft Rejection/diagnosis
  • Ventricular Function, Left
  • Humans
  • Myocardial Infarction/complications
  • Intra-Aortic Balloon Pumping/instrumentation
  • Recovery of Function
  • Young Adult
  • Heart Failure/diagnosis
  • Extracorporeal Membrane Oxygenation
  • Female
  • Shock, Cardiogenic/diagnosis
  • Heart-Assist Devices
  • Models, Cardiovascular
  • Risk Factors
  • Cardiotonic Agents/therapeutic use
  • Treatment Outcome
  • Stroke Volume
  • Heart Transplantation/adverse effects
  • Aged
  • Ventricular Pressure
  • Ventricular Function, Right

ASJC Scopus subject areas

  • Medicine(all)


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