Phosphorylation of protein inhibitor of activated STAT1 (PIAS1) by MAPK-activated protein kinase-2 inhibits endothelial inflammation via increasing both PIAS1 transrepression and SUMO E3 ligase activity

Kyung-Sun Heo, Eugene Chang, Yuichiro Takei, Nhat-Tu Le, Chang-Hoon Woo, Mark A Sullivan, Craig Morrell, Keigi Fujiwara, Jun-ichi Abe

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Biochemistry, Genetics and Molecular Biology

Pharmacology, Toxicology and Pharmaceutical Science