Phospholipids in Biology and Medicine

Richard L. Jackson, Antonio Gotto

Research output: Contribution to journalReview article

17 Scopus citations

Abstract

PHOSPHOLIPIDS, which are important in the structure and function of biologic membranes, have been the subject of evolving information correlating their physical and chemical properties with their physiologic role. An earlier held concept of phospholipids as static structural components of membranes has been dispelled. Phospholipids are in a dynamic state within the membrane, and they may undergo physico-chemical changes. A major aim of this review is to relate this pleomorphism of phospholipids to the biologic properties of membrane and plasma lipoproteins. We have not considered the synthesis and catabolism of phospholipids, a subject discussed by McMurray and Magee.1 Phospholipids are.

Original languageEnglish (US)
Pages (from-to)24-29
Number of pages6
JournalNew England Journal of Medicine
Volume290
Issue number1
DOIs
StatePublished - Jan 3 1974

ASJC Scopus subject areas

  • Medicine(all)

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