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Peritoneal Immunosurgery: Immunotherapy Augmented Surgery for the Treatment of Peritoneal Cancers

Ada I. Ozcan, Arianexys Aquino López, Mary K. McKenna, Malcolm K. Brenner, Alastair M. Thompson

Research output: Contribution to journalReview articlepeer-review

Abstract

Peritoneal malignancy often indicates disruptions in multiple physiological systems resulting from widespread cancer. The heterogenous origin and dynamic nature of peritoneal cancer make it difficult to treat with standard approaches that fit into guidelines. We describe how successful treatment should address the underlying pathology, the systemic response to surgical treatments and target the immune perturbations that facilitate the establishment and propagation of this multifaceted disease.

Original languageEnglish (US)
Pages (from-to)789-809
Number of pages21
JournalJournal of Surgical Oncology
Volume132
Issue number5
DOIs
StatePublished - Oct 2025

Keywords

  • immunotherapy
  • peri-operative immunity
  • peritoneal cancer
  • peritoneum
  • surgery

ASJC Scopus subject areas

  • Surgery
  • Oncology

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