TY - JOUR
T1 - PERIPHERAL RETINAL ANGIOGRAPHIC FINDINGS IN MACULAR TELANGIECTASIS TYPE 2
AU - Moysidis, Stavros N.
AU - Koulisis, Nicole
AU - Rao, Prethy
AU - Govindaraju, Viren K.
AU - Gamsky, Samuel
AU - Mahmoud, Tamer H.
AU - Randhawa, Sandeep
AU - Faia, Lisa J.
AU - Wolfe, Jeremy D.
AU - Drenser, Kimberly A.
AU - Ruby, Alan J.
AU - Garretson, Bruce R.
AU - Hassan, Tarek S.
AU - Williams, George A.
AU - Trese, Michael T.
AU - Capone, Antonio
N1 - Publisher Copyright:
© 2021 Lippincott Williams and Wilkins. All rights reserved.
PY - 2021/3/1
Y1 - 2021/3/1
N2 - Purpose:To evaluate the retinal periphery in patients with idiopathic juxtafoveal telangiectasis or macular telangiectasis Type 2 (MacTel2), using widefield fluorescein angiography.Methods:Single-center, retrospective, observational case series of 50 eyes of 50 patients with MacTel2 and 50 eyes of 50 age-matched controls.Results:Thirty-seven eyes in the MacTel2 group (74%) showed peripheral capillary nonperfusion or dropout, compared with 37 eyes in the control group (74%, P = 1.0). Morphologically, the MacTel2 group trended toward having a higher proportion of pruning-type capillary dropout (44%) compared with controls (28%), but this was not statistically significant (P = 0.12). Patients with MacTel2 had a higher incidence of microaneurysms compared with controls (MacTel2 56%; controls 42%; P = 0.048), independent of age or systemic risk factors. There was no difference in the incidence of venous-venous shunts (MacTel2 10%; controls 10%; P = 1.0), arteriovenous shunts (MacTel2 14%; controls 18%; P = 0.60), venous tortuosity (MacTel2 60%; controls 66%; P = 0.58), or arterial tortuosity (MacTel2 54%; controls 68%; P = 0.20), which was mild in most cases.Conclusion:We note a high incidence of peripheral vascular and retinal findings in both patients with MacTel2 and age-matched controls, using widefield fluorescein angiography. Patients with MacTel2 had significantly more microaneurysms, independent of age or other systemic risk factors.
AB - Purpose:To evaluate the retinal periphery in patients with idiopathic juxtafoveal telangiectasis or macular telangiectasis Type 2 (MacTel2), using widefield fluorescein angiography.Methods:Single-center, retrospective, observational case series of 50 eyes of 50 patients with MacTel2 and 50 eyes of 50 age-matched controls.Results:Thirty-seven eyes in the MacTel2 group (74%) showed peripheral capillary nonperfusion or dropout, compared with 37 eyes in the control group (74%, P = 1.0). Morphologically, the MacTel2 group trended toward having a higher proportion of pruning-type capillary dropout (44%) compared with controls (28%), but this was not statistically significant (P = 0.12). Patients with MacTel2 had a higher incidence of microaneurysms compared with controls (MacTel2 56%; controls 42%; P = 0.048), independent of age or systemic risk factors. There was no difference in the incidence of venous-venous shunts (MacTel2 10%; controls 10%; P = 1.0), arteriovenous shunts (MacTel2 14%; controls 18%; P = 0.60), venous tortuosity (MacTel2 60%; controls 66%; P = 0.58), or arterial tortuosity (MacTel2 54%; controls 68%; P = 0.20), which was mild in most cases.Conclusion:We note a high incidence of peripheral vascular and retinal findings in both patients with MacTel2 and age-matched controls, using widefield fluorescein angiography. Patients with MacTel2 had significantly more microaneurysms, independent of age or other systemic risk factors.
KW - JXT
KW - MacTel2
KW - aging
KW - idiopathic parafoveal juxtafoveal telangiectasis
KW - macular telangiectasis Type 2
KW - multimodal imaging
KW - ocular manifestations of systemic disease
KW - optical coherence tomography
KW - retinal periphery
KW - retinal vascular pathology
KW - widefield fluorescein angiography
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U2 - 10.1097/IAE.0000000000002981
DO - 10.1097/IAE.0000000000002981
M3 - Article
C2 - 32969983
AN - SCOPUS:85102212334
SN - 0275-004X
VL - 41
SP - 480
EP - 486
JO - Retina
JF - Retina
IS - 3
ER -