TY - JOUR
T1 - Performance of rupture-related morphological parameters in posterior communicating artery aneurysms with fetal-type variant
AU - Chen, S.
AU - Li, C.
AU - Karmonik, C.
AU - Cheng, Y.
AU - Lv, N.
N1 - Funding Information:
This study was funded by the National Research and Development Project of Key Chronic Diseases (Grant No. 2016YFC1300700) and National Natural Science Foundation of China (Grant Nos. 81701775 and 81771264).
Publisher Copyright:
© 2023 Via Medica
PY - 2023
Y1 - 2023
N2 - BACKGROUND: The aim of the study was to investigate the impact of fetal-type posterior cerebral artery (fPCA) variant on morphological parameters of posterior communicating artery (PComA) aneurysms for rupture risk assessment.MATERIALS AND METHODS: A total of 98 PComA aneurysms (62 ruptured and 36 unruptured) in 98 consecutive patients were reviewed. Morphological parameters were calculated including aneurysm size, aspect ratio (AR), size ratio (SR), dome-to-neck ratio, bottleneck factor and inflow angle. Performances of morphological parameters to discriminate rupture status were compared between aneurysms with or without fPCA.RESULTS: Fetal-type posterior cerebral artery variant was determined in 39 (39.8%, 25 ruptured and 14 unruptured) lesions. The ruptured group revealed a significantly larger size (p = 0.004), AR (p = 0.003), SR (p = 0.001), and inflow angle (p < 0.001). For the aneurysms without fPCA, all morphological parameters were significantly different between ruptured and unruptured aneurysms (p < 0.05); for the aneurysms with fPCA, only inflow angle (p = 0.001) was significantly related with the rupture status. Multivariate analysis showed that SR (p = 0.035 and p = 0.011) and inflow angle (p = 0.001 and p = 0.028) were independent rupture risk factors for the total cohort and the aneurysms without fPCA; while only inflow angle (p = 0.004) revealed to be independently related with rupture status of aneurysms without fPCA.CONCLUSIONS: The performances of morphological parameters to discriminate rupture status were different between PComA aneurysms with and without fPCA variants. Inflow angle might be a reliable predictor for rupture risk of PComA aneurysms.
AB - BACKGROUND: The aim of the study was to investigate the impact of fetal-type posterior cerebral artery (fPCA) variant on morphological parameters of posterior communicating artery (PComA) aneurysms for rupture risk assessment.MATERIALS AND METHODS: A total of 98 PComA aneurysms (62 ruptured and 36 unruptured) in 98 consecutive patients were reviewed. Morphological parameters were calculated including aneurysm size, aspect ratio (AR), size ratio (SR), dome-to-neck ratio, bottleneck factor and inflow angle. Performances of morphological parameters to discriminate rupture status were compared between aneurysms with or without fPCA.RESULTS: Fetal-type posterior cerebral artery variant was determined in 39 (39.8%, 25 ruptured and 14 unruptured) lesions. The ruptured group revealed a significantly larger size (p = 0.004), AR (p = 0.003), SR (p = 0.001), and inflow angle (p < 0.001). For the aneurysms without fPCA, all morphological parameters were significantly different between ruptured and unruptured aneurysms (p < 0.05); for the aneurysms with fPCA, only inflow angle (p = 0.001) was significantly related with the rupture status. Multivariate analysis showed that SR (p = 0.035 and p = 0.011) and inflow angle (p = 0.001 and p = 0.028) were independent rupture risk factors for the total cohort and the aneurysms without fPCA; while only inflow angle (p = 0.004) revealed to be independently related with rupture status of aneurysms without fPCA.CONCLUSIONS: The performances of morphological parameters to discriminate rupture status were different between PComA aneurysms with and without fPCA variants. Inflow angle might be a reliable predictor for rupture risk of PComA aneurysms.
KW - intracranial aneurysm
KW - morphology
KW - rupture
KW - Intracranial Aneurysm/complications
KW - Humans
KW - Retrospective Studies
KW - Cerebral Angiography/adverse effects
KW - Aneurysm, Ruptured/etiology
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U2 - 10.5603/FM.a2021.0123
DO - 10.5603/FM.a2021.0123
M3 - Article
C2 - 34783002
AN - SCOPUS:85148672121
SN - 1644-3284
VL - 82
SP - 30
EP - 36
JO - Folia morphologica
JF - Folia morphologica
IS - 1
ER -