Penfluridol: A long acting oral antipsychotic drug

J. L. Claghorn, R. J. Mathew, Mohsen Mirabi

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Penfluridol is a diphenylbutylpiperdine derivative with a half-life of 66 hours. The present study was designed to determine its efficacy for the maintenance of schizophrenia. In a 52 week double-blind study, once weekly doses of penfluridol were compared with once daily doses of chlorpromazine in 56 schizophrenic patients receiving maintenance treatment on an outpatient basis. Both drugs were similar in their clinical effectiveness; no major side effects occurred with either drug.

Original languageEnglish (US)
Pages (from-to)107-109
Number of pages3
JournalJournal of Clinical Psychiatry
Issue number2
StatePublished - Jan 1 1979

ASJC Scopus subject areas

  • Psychiatry and Mental health


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