Pediatric recurrent laryngeal nerve reinnervation: A case series and analysis of post-operative outcomes

Zachary Farhood, Nicole M. Reusser, Robert W. Bender, Apurva A. Thekdi, James Albright, Joseph Edmonds

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


Objective: To provide detailed information about recurrent laryngeal nerve (RLN) reinnervation outcomes in children using objective measures. Methods: The records of three pediatric patients with unilateral vocal cord paralysis that underwent RLN reinnervation were retrospectively reviewed. Fundamental frequency (F0), jitter, shimmer, noise-to-harmonic ratio (NHR), and voice phonation (sustained /s/, /z/, /a/) were measured preoperatively and post-operatively at 13, 9, and 33 months (each time period corresponding to one of the three patients). Results: Mean preoperative and post-operative variables were as follows: shimmer, 9.65±1.02% vs. 4.46±0.71% (p=0.01); NHR, 0.296±0.063 vs. 0.127±0.011 (p=0.04); jitter, 3.57±0.89% vs. 1.46±0.54% (p=0.08); F0, 274.6±35.4Hz vs. 282.2±70.6Hz (p=0.44); maximum phonation time, 7.46±1.40s vs. 9.79±1.84s (p=0.22); /s:z/ ratio, 1.28±0.22 vs.1.07±0.09 (p=0.26). Conclusions: There was statistically significant improvement in shimmer and NHR. Jitter improvement approached statistical significance. All other variables failed to show significant improvement among this small sample size. RLN reinnervation for pediatric patients is an option for the treatment of vocal cord paralysis. Further studies with larger cohorts are needed to show the full benefits.

Original languageEnglish (US)
Pages (from-to)1320-1323
Number of pages4
JournalInternational Journal of Pediatric Otorhinolaryngology
Issue number8
StatePublished - 2015


  • Cord paralysis
  • Laryngeal reinnervation
  • Surgery
  • Vocal fold

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Otorhinolaryngology


Dive into the research topics of 'Pediatric recurrent laryngeal nerve reinnervation: A case series and analysis of post-operative outcomes'. Together they form a unique fingerprint.

Cite this